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Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

Study unravels the DNA repair mechanism by enzymes

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Smoking-related DNA methylation patterns explain the variation in BMI between individuals

Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh.

13 Sep 2021

Viruses buried in marsupials' DNA may help protect against future infections

Fossils of ancient viruses are preserved in the genomes of all animals, including humans, and have long been regarded as junk DNA. But are they truly junk, or do they actually serve a useful purpose?

From The University of New South Wales (UNSW) 9 Sep 2021

Functional genomics can assist in molecular breeding of maize, finds study

For centuries, the vast physical diversity of maize, the most popular cereal grain crop globally, has fascinated biologists and plant breeders alike.

9 Sep 2021

Study imparts mechanistic understanding on early stages of human cancer

Scientists demonstrated that normal human fibroblast cells can be converted to specific cancer cells through factors that are identified in actual human patients.

9 Sep 2021

Study unearths previously unknown role of CTCF, the transcription regulator

Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.

9 Sep 2021

Bacteria-derived curli amyloid fibril promotes neurodegeneration in the host

Increasing evidence points to the fact that gut microbiota performs a vital role in regulating the advancement of neurodegenerative diseases like Alzheimer’s.

9 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Drug-resistant Salmonella serovar Enteritidis genome sequenced by experts

Scientists sequenced the genome of a virulent Salmonella Enteritidis strain and discovered that it was both antibiotic-resistant and could affect people.

7 Sep 2021

Study provides deep insights into the association between genes and diseases

Scientists examined genomic data from more than 30,000 individuals and unraveled thousands of new regulatory regions that regulate disease-linked genes.

7 Sep 2021

Researchers discover the role of a retrotransposon in horizontal memory transfer in roundworms

When an organism encounters a threat in its environment, it is to the species' advantage to warn others of the peril.

6 Sep 2021

Plant bulbs harboring lethal pathogen make the perfect lab for evolving drug-resistant strains

Just when we thought it was safe to go to the local garden center, researchers from Japan have discovered that fungicide-resistant strains of a nasty pathogen have been getting up to no good among the tulip bulbs.

6 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Scientists develop data analysis platform to enhance apple breeding process

A new platform housing data from over 100 apple varieties could shave years off of the breeding process and enable data-driven assessments of how to boost the health benefits of America's favorite fruit.

3 Sep 2021

Researchers discover new pathway used by cells to remove cellular waste

In a new study, researchers have identified a new pathway that cells use to eliminate cellular waste that otherwise would damage the cell’s genes.

3 Sep 2021

Insights on cross-resistance can improve potency of sequential antibiotic treatment

A new study notes that sequential treatment with antibiotics that are similar but often swapped around can effectively kill bacteria and avoid drug resistance.

2 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

New algorithm can identify diseased cells for personalized treatment

Scientists have created an innovative artificial intelligence algorithm known as “scArches” for clinical applications.

1 Sep 2021

Genome News and Research

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Study unravels the DNA repair mechanism by enzymes

Smoking-related DNA methylation patterns explain the variation in BMI between individuals

Viruses buried in marsupials' DNA may help protect against future infections

Functional genomics can assist in molecular breeding of maize, finds study

Study imparts mechanistic understanding on early stages of human cancer

Study unearths previously unknown role of CTCF, the transcription regulator

Bacteria-derived curli amyloid fibril promotes neurodegeneration in the host

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

Drug-resistant Salmonella serovar Enteritidis genome sequenced by experts

Study provides deep insights into the association between genes and diseases

Researchers discover the role of a retrotransposon in horizontal memory transfer in roundworms

Plant bulbs harboring lethal pathogen make the perfect lab for evolving drug-resistant strains

Miniature CRISPR-Cas system expands applicability and implications further

Scientists develop data analysis platform to enhance apple breeding process

Researchers discover new pathway used by cells to remove cellular waste

Insights on cross-resistance can improve potency of sequential antibiotic treatment

Genetically engineered cells deliver drugs in response to inflammation

New algorithm can identify diseased cells for personalized treatment

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