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Electron cryo-microscopy sheds light on how bioenergy makers are made in our body

Mitochondria are organelles that act as the powerhouses in our body. They use oxygen which we inhale and the food we eat to produce energy that supports our life.

22 Feb 2021

Advanced explainable AI to solve regulatory instructions encoded in DNA

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical tour de force to decipher regulatory instructions encoded in DNA.

19 Feb 2021

Genetic testing technology is extremely unreliable in detecting very rare genetic variants

According to a new study, a technology that is extensively used by commercial genetic testing firms is “extremely unreliable” in identifying very rare variants.

From University of Exeter 16 Feb 2021

Antioxidant in green tea may lead to new anti-cancer drugs

Green tea contains an antioxidant that may boost the concentrations of p53, called the “guardian of the genome,” for its potential to kill cancerous cells.

15 Feb 2021

Study uncovers how harmless E.coli gut bacteria turn deadly

An international team of scientists has determined how harmless E.coli gut bacteria in chickens can easily pick up the genes required to evolve to cause a life-threatening infection.

From University of Bath 15 Feb 2021

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.

15 Feb 2021

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease.

12 Feb 2021

Daytime napping is partly regulated by a person's genes

How often a person takes daytime naps, if at all, is partly regulated by their genes, according to new research led by investigators at Massachusetts General Hospital (MGH) and published in Nature Communications.

11 Feb 2021

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors cannot accurately predict which of their patients will respond.

11 Feb 2021

Study examines the largest and most diverse genetic sequencing data sets

Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority populations.

11 Feb 2021

Researchers program genome tool to target specific histone proteins

If finding a needle in a haystack is hard enough, then one should try finding a particular molecule on the needle.

11 Feb 2021

Unusual DNA folding leads to higher mutation rates

DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome.

From Penn State University 10 Feb 2021

New study facilitates the use of gene editing technique on plants

A new study performed by the IBMCP of UPV University enables the use of the CRISPR genomic editing technique on plants.

9 Feb 2021

New platform may accelerate genomic medicine research, drug therapies

A research team, headed by Cleveland Clinic, has designed a novel personalized genomic medicine platform that would help speed up genomic medicine studies as well as genome-informed drug discovery. The results of the new study have been recently published in the Genome Biology journal.

9 Feb 2021

Researchers identify three genes regulating stemness of gastric tissue stem cells

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages.

9 Feb 2021

New bioinformatic tool allows scientists to digitally genotype sequenced populations

With the recently developed bioinformatic tool, called SSRgenotyper, scientists can now use simple sequence repeats to digitally genotype sequenced populations.

9 Feb 2021

Researchers identify genes that determine a person’s facial profile

A research team, headed by the University College London, has discovered genes that establish the shape of an individual’s facial profile.

From University College London 9 Feb 2021

Hidden genes in bacteriophages may be key to the development of new antibiotics

A study from the Center for Phage Technology, part of Texas A&M's College of Agriculture and Life Sciences and Texas A&M AgriLife Research, shows how the "hidden" genes in bacteriophages -- types of viruses that infect and destroy bacteria -- may be key to the development of a new class of antibiotics for human health.

8 Feb 2021

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele.

5 Feb 2021

Genome News and Research

Electron cryo-microscopy sheds light on how bioenergy makers are made in our body

Advanced explainable AI to solve regulatory instructions encoded in DNA

Genetic testing technology is extremely unreliable in detecting very rare genetic variants

Antioxidant in green tea may lead to new anti-cancer drugs

Study uncovers how harmless E.coli gut bacteria turn deadly

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Daytime napping is partly regulated by a person's genes

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

Study examines the largest and most diverse genetic sequencing data sets

Researchers program genome tool to target specific histone proteins

Unusual DNA folding leads to higher mutation rates

New study facilitates the use of gene editing technique on plants

New platform may accelerate genomic medicine research, drug therapies

Researchers identify three genes regulating stemness of gastric tissue stem cells

New bioinformatic tool allows scientists to digitally genotype sequenced populations

Researchers identify genes that determine a person’s facial profile

Hidden genes in bacteriophages may be key to the development of new antibiotics

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

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