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Researchers identify genes associated with autism spectrum disorder

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide (CSIC-UPO).

27 Oct 2020

Cellular senescence variations may help control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Novel machine learning algorithm helps identify binding sites in drug targets

Scientists from the iMolecule group at Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) developed BiteNet, a machine learning (ML) algorithm that helps find drug binding sites, i.e. potential drug targets, in proteins.

27 Oct 2020

Researchers identify new potential therapeutic targets for SARS-CoV-2 infection

To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome.

27 Oct 2020

Scientists explain the role of transcription factors in genetic diseases

Transcription factor proteins can be described as the light switches of the human genome. These proteins bind to DNA and allow genes to turn “on” or “off.”

26 Oct 2020

Study: Early travel restrictions have significantly limited the spread of COVID-19 virus

The coronavirus, responsible for the COVID-19 pandemic, has one official name--SARS-CoV-2. But according to virologists, mutations lead to hundreds of genetically-distinct versions of the virus.

23 Oct 2020

Researchers develop "mini lungs" to study SARS-CoV-2 infection

'Mini-lungs' grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs.

23 Oct 2020

Study raises ethical concerns about gene-editing technologies

Genome editing of human embryos represents one of the most contentious potential scientific applications today. But what if geneticists could sidestep the controversy by editing sperm and eggs instead?

22 Oct 2020

Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

The virus wreaking havoc on our lives is an efficient infection machine. Comprised of only 29 proteins (compared to our 400,000), with a genome 1/200,000 the size of ours, SARS-CoV-2 is expertly evolved to trick our cells to contribute its machinery to assist in its propagation.

22 Oct 2020

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

22 Oct 2020

New research indicates the link between diabetes and SARS-CoV-2 viral infection

Recently, researchers explained that infection by certain enteroviruses could possibly activate diabetes.

22 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Study explores the impact of microbial immune diversity on dynamics of host-virus interactions

CRISPR-Cas serves as a key driving force of strain diversity in host-virus systems during an evolutionary fight between the host and virus.

21 Oct 2020

First-ever draft sequence of the human proteome mapped successfully

Two decades after the release of the human genome, researchers have mapped the first-ever draft sequence of the human proteome.

21 Oct 2020

Researchers develop new method to advance wildlife genomics

A team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), the Australian Museum, and the Max Delbrück Center for Molecular Medicine (MDC) report a new method for identifying any genome sequence located next to a known sequence.

20 Oct 2020

Researchers identify “silent” mutations in the genetic code of COVID-19 virus

We know that the coronavirus behind the COVID-19 crisis lived harmlessly in bats and other wildlife before it jumped the species barrier and spilled over to humans.

19 Oct 2020

CRISPR platform can accelerate potential treatment targets for SARS-CoV-2

Synthego has provided multiple CRISPR-based engineered cell lines to speed up the analysis of promising treatment targets for SARS-CoV-2.

19 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

16 Oct 2020

Study sheds light on whether corals are genetically equipped to handle warmer oceans

In 1998, ocean temperatures soared, and the world experienced its first significant coral bleaching event. From the Great Barrier Reef to Indonesia to Central America, corals turned white and ghostly.

15 Oct 2020

DNA structural changes play key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).

15 Oct 2020