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New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Novel genetic measure could improve screening for osteoporosis

An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility.

22 Jul 2020

Researchers comprehensively describe the 'human tissue virome atlas'

Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.

22 Jul 2020

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

22 Jul 2020

Researchers use high-quality coral genome to forecast potential bleaching events

In a new approach to conservation genetics, researchers used a high-quality genome of the coral Acropora millepora, along with environmental data, to study this coral's variable responses to climate change, a trait of key conservation importance.

17 Jul 2020

Study shows genetic factors may influence the susceptibility to COVID-19

A new Cleveland Clinic study has identified genetic factors that may influence susceptibility to COVID-19. Published today in BMC Medicine, the study findings could guide personalized treatment for COVID-19.

16 Jul 2020

Genomics study in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

13 Jul 2020

Scientists report detailed proteomic analysis of human lung adenocarcinoma

A team of Chinese scientists from the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, the State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Shanghai Jiao Tong University, recently reported a comprehensive proteomic analysis based on 103 Chinese patients with lung adenocarcinoma (LUAD), a leading cause of death among all types of cancer worldwide.

10 Jul 2020

Study explains why human mitochondrial genomes mutate frequently

One could say that mitochondria, the energy-producing organelles inside every human cell, dance to their own beat.

10 Jul 2020

Report highlights role of genomics in perpetuating racism and inequality

Genomics is crowding out ways of reducing inequality, has thwarted medicine from advancing justice, and is creating new forms of social classification and surveillance.

9 Jul 2020

New spatial mapping method pinpoints new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

9 Jul 2020

Plant tissue succulence engineering can be used to improve drought and salinity tolerance

After several years of experimentation, scientists have engineered thale cress, or Arabidopsis thaliana, to behave like a succulent, improving water-use efficiency, salinity tolerance and reducing the effects of drought.

3 Jul 2020

Region-specific atlas reveals genome linked to human embryonic brain development

An adjusted sequence of genetic events should occur to allow the budding brain of a human embryo to turn into the organ that regulates human consciousness.

1 Jul 2020

Engineered T-cells attack solid-tumor cancer cells from humans and mice

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia.

1 Jul 2020

Rapid genomic profiling of colon cancers can improve therapy

Genomic mutation testing is critical to the therapeutic selection and management of patients with colorectal cancer.

29 Jun 2020

Single-cell sequencing can reveal genetic diversity of cancer cells

In the past, the potential to sequence the genome of the tumor has redefined the treatment of cancer by detecting cancer drivers at the molecular level.

26 Jun 2020

Helping to unravel the genetic diversity of cancer tumors

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the years by identifying drivers of cancer at the molecular level.

26 Jun 2020

Genome study opens pathway toward sustainable edible seaweed

Since the 1980s, in seaweed farms dotted along the coastline of the subtropical islands of Okinawa, farmers have cultivated the edible brown alga.

26 Jun 2020

Super-resolution technology helps visualize DNA replication in single human cells

DNA replication is a process of critical importance to the cell, and must be coordinated precisely to ensure that genomic information is duplicated once and only once during each cell cycle.

26 Jun 2020

Whole genome sequencing can improve rare disease diagnosis

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

25 Jun 2020

Genomic News and Research

New startup launched to overcome the challenge of delivering next-generation therapeutics

Novel genetic measure could improve screening for osteoporosis

Researchers comprehensively describe the 'human tissue virome atlas'

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Researchers use high-quality coral genome to forecast potential bleaching events

Study shows genetic factors may influence the susceptibility to COVID-19

Genomics study in Black Americans could lead to precision prostate cancer therapies

Scientists report detailed proteomic analysis of human lung adenocarcinoma

Study explains why human mitochondrial genomes mutate frequently

Report highlights role of genomics in perpetuating racism and inequality

New spatial mapping method pinpoints new potential therapeutic targets for lupus

Plant tissue succulence engineering can be used to improve drought and salinity tolerance

Region-specific atlas reveals genome linked to human embryonic brain development

Engineered T-cells attack solid-tumor cancer cells from humans and mice

Rapid genomic profiling of colon cancers can improve therapy

Single-cell sequencing can reveal genetic diversity of cancer cells

Helping to unravel the genetic diversity of cancer tumors

Genome study opens pathway toward sustainable edible seaweed

Super-resolution technology helps visualize DNA replication in single human cells

Whole genome sequencing can improve rare disease diagnosis

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