Glioma News and Research

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Glioma is a cancer of the brain that begins in glial cells (cells that surround and support nerve cells).

RNA Splicing Errors May Hold the Key to Beating Gliomas Using Immunotherapy

Identifying splicing-related neoantigens in gliomas opens new avenues for immunotherapy, enhancing treatment strategies for this challenging brain tumor.

26 Feb 2025

Immunotherapy Breakthrough Targets Jumbled Proteins in Glioma

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

20 Feb 2025

AI Model 'MUSK' Advances Cancer Diagnosis with Multimodal Data Integration

MUSK, a vision-language model, enhances cancer diagnosis by integrating multimodal data, outperforming existing methods in prognosis and treatment predictions.

23 Jan 2025

Immunotherapy Advances: CAR T Cells Targeting GD2 Offer Hope for Glioma Patients

Findings suggest GD2-specific CAR T-cell therapy is a viable option for H3K27M-mutant gliomas, with significant tumor shrinkage and clinical benefits observed.

22 Nov 2024

A New Technique Reveals the Behavior of OPCs in the Brain

Imagine yourself sometime in the far future aboard a routine rocket to Mars. Someone just spilled their drink. Without gravity, it collects in floating blobs that ripple right before your eyes. Now freeze.

14 Oct 2024

Unlocking Glucose-Driven Mechanisms of Immunosuppression in Glioblastoma

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

6 May 2024

Non-Invasive Early Cancer Detection Using Chromatin Signatures in Mononuclear Blood Cells

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

18 Dec 2023

Analyzing Glioma Progression and Implicating CPNs’ Long-Range Projections

Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. Despite treatment, GBM recurrence is inevitable and tends to occur outside surgical margins or in locations remote to the primary tumor, highlighting the central role played by tumor infiltration in this malicious disease.

29 Jun 2023

Potential Therapy for Lethal Pediatric Brain Cancer Using ASO Technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

13 Apr 2023

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

24 Mar 2023

LDL-mediated nanoparticle drug delivery could potentially circumvent high-grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

8 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

New molecular understanding of how head injury may contribute to glioma risk

Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.

27 Feb 2023

IGSF3-mediated potassium dysregulation drives glioma-related epilepsy

Glioma is one of the most aggressive malignant primary brain tumors. A common feature of glioma is the presence of localized, intermittent seizures referred to as glioma-related epilepsy, which is known to promote tumor growth. However, the mechanism involved at the molecular level is still not clear.

15 Feb 2023