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Realistic model explores new treatments for brain tumors

Until now, the use of models to study the barrier that differentiates the circulatory and nervous systems has been either limited or extremely complex. ETH Zurich researchers have created a more accurate model that can also be used to effectively investigate new treatments for brain tumors.

21 Feb 2023

The essential protein needed for immune evasion and tumor cell metabolism

Typically, tumor cells change their energy metabolism and take in more glucose to enable their rapid division and spread. As a result, the body’s immune response to cancer is suppressed by limiting the immune cells’ access to glucose.

15 Feb 2023

Pancreatic islet microexons play key role in islet function and glucose homeostasis

When cells copy DNA to produce RNA transcripts, they include only some chunks of genetic material known as exons and throw out the rest.

10 Feb 2023

The correlation between Type 2 diabetes and human microRNAs

Although it has long been believed that microRNA (miRNA) molecules in pancreatic islets play significant roles in Type 2 diabetes, no specific miRNAs have been definitively linked to the disease in humans.

10 Feb 2023

Innovative cancer therapy options with new cell death mechanism

Researchers from The University of Texas MD Anderson Cancer Center have described a previously unrecognized type of cell death called disulfidptosis in a study that was published in Nature Cell Biology.

7 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity."

1 Feb 2023

The continued functioning of circadian clock of cells even after starvation

According to a study that was just published in eLife, cells that have a functioning molecular clock are better able to adapt to changes in glucose supply and can recover from long-term starvation more quickly.

11 Jan 2023

Analyzing the regulatory mechanisms of enzyme production in mold

Filamentous fungi have long been a close ally of sake brewers, but they may soon become associates of environmentalists as well. Scientists from Osaka Metropolitan University discovered the regulatory mechanisms of enzyme synthesis in a filamentous fungus, allowing for the effective degradation of plant biomass, an alternative energy resource to petroleum.

11 Jan 2023

What are the implications of microbiome-directed measures to treat type 2 diabetes?

According to preliminary findings from an ongoing, prospective study headed by Cedars-Sinai researchers, one type of bacteria seen in the gut might contribute to the development of Type 2 diabetes, while another might guard against the condition.

5 Jan 2023

Pill-shaped ingestible biosensing system enables continuous monitoring in the intestinal environment

Engineering researchers have developed a battery-free, pill-shaped ingestible biosensing system designed to provide continuous monitoring in the intestinal environment.

6 Dec 2022

Novel proteomics approach to identify a three-protein signature in the blood

A new proteomics method has been utilized by researchers to determine a three-protein signature in the blood that has the potential to enhance the detection of separated impaired glucose tolerance, a form of prediabetes.

14 Nov 2022

Researchers discover murderous survival strategy of yeast

Yeast is not the simple single-celled microorganism we once thought, but a competitive killer. When starved of glucose, yeast releases a toxin that will poison other microorganisms that have entered its surrounding habitat, even its own clones.

8 Nov 2022

Georgia Tech researchers develop a new biomaterial that could cure Type 1 diabetes

Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges.

4 Nov 2022

A new outlook on sow breeding using dietary nucleotides

The primary fetal organ systems’ growth and development are strongly influenced by the nutrition status of the mother. Late gestation is when fetal growth is rapidly accelerated, and the nutritional needs of sows rise dramatically as a result of the fetus’ rapid growth and the placenta’s quick expansion.

26 Oct 2022

A strong enzyme that functions similar to a Swiss army knife

Blue-green algae, also known as cyanobacteria, have a superpower that likely contributes to their extreme success as waterway invaders. They have a remarkable capacity to store nitrogen and energy in their cells for use when necessary.

3 Oct 2022

The exchange of nutrients between the mother and fetus mirrored by ‘placenta-on-a-chip’

Plasmodium falciparum infections can result in placental malaria, which can have serious consequences for both mother and child. Nearly 200,000 newborn fatalities annually from placental malaria, primarily as a result of low birth weight, as well as 10,000 maternal deaths.

27 Sep 2022