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Bile salt hydrolase cocktails may offer a new approach to inhibit C. diff colonization

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

14 Mar 2023

New biomarker helps identify biological age

Once considered to be incompetent in encoding proteins due to their simple monotonous DNA repetitions, tiny telomeres at the tips of human chromosomes now appear to have a powerful biological function that could help better understand cancer and aging.

21 Feb 2023

Significance of aerial root nutrient uptake in indoor plant growth

Most people own houseplants and eagerly grow them on windowsills and shelves only to be disappointed when they wilt or die - new research has shown that the problem could be that we're feeding them all wrong and we need to pay attention to the roots outside the soil.

16 Feb 2023

New route to understanding the origins of life

A team of scientists from France and Austria has discovered a new abiotic pathway for the formation of peptide chains from amino acids - a key chemical step in the origin of life.

13 Feb 2023

Researchers get funding to develop a vaccine against ALS disease

DZNE and Intravacc B.V., have received a grant from the European Union of € 2.5 million to further create a prototype ALS vaccine.

8 Jul 2022

Novel platform enables sequence-unconstrained traceless protein synthesis

According to recent research published a multi-enzyme platform was created for sequence-unconstrained traceless protein synthesis and modification.

26 Oct 2021

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

CMT, a rare hereditary condition, commences when genetic changes interrupt the transmission of nerve signals from the brain to the muscles of the extremities, specifically those of the lower limbs.

16 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Small synthetic molecules could one day cure or prevent COVID-19, herpes

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.

24 Aug 2021

New study uncovers how enterococcal cytolysins affect cells

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so.

22 Jul 2021

Simple 'designer' pore reproduces selective cellular transport mechanisms

The nucleus is the headquarters of a cell and molecules constantly move across the nuclear membrane through pores. The transport of these molecules is both selective and fast; some 1,000 molecules per second can move in or out.

31 Mar 2021

Study reveals link between group of metabolites in blood and satiety perception

Results of the European study SATIN (SATiety INnovation) reveal a relation between certain metabolites in the blood and the satiety perceived after consuming food.

23 Feb 2021

Study reveals novel dimension in the study of protein-protein interactions

Many proteins are required to maintain the structure, and to preserve the genetic integrity, of DNA. Sliding clamps are proteins that increase the efficiency of DNA replication.

11 Dec 2020

Scientists elucidate the structure of ABC transporter protein

A high concentration of salt or sugar in the environment will dehydrate microorganisms and stop them from growing.

19 Nov 2020

Researchers discover how tomato plants identify Cuscuta as a parasite

Working together with researchers from the University of Tübingen, the University of Tromsø, the UC Davis and the Sainsbury Laboratory in Norwich, biologists from Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) have discovered how tomato plants identify Cuscuta as a parasite.

5 Nov 2020