Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.
A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.
Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).
Professor Yuichi Oike and his group of researchers recently produced a peptide vaccine that mitigates conditions of dyslipidemia.
The Centers for Disease Control and Prevention states that heart failure impacts over six million Americans and is the major reason for death.
Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.
A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.
A research group led by Massachusetts General Hospital has developed premature cells that promote early heart development but disappear soon after birth.
Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.
Recent research identified that a protein involved in regulating calcium signaling within heart cells can play a vital role in the prevention of chronic heart failure.
Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.
The origin of rare, severe muscle disease has been uncovered by an international team of researchers headed by the University of Bonn (Germany).
It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a new study, researchers from the University of Tsukuba have shown how cells in the scar tissue can be converted to heart muscle cells, effectively regenerating the injured heart.
Skeletal muscle makes up 30% to 40% of body weight and serves multiple functions like heat production and energy metabolism.
Doctors often recommend Omega-3s to help patients lower their cholesterol and improve heart health. Those Omega-3s can come from fatty fish like salmon and mackerel, or supplements that often contain a combination of the acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
If someone craves a strong caffeine hit or like the frothiness of a milky cappuccino, their daily coffee order can reveal more about their health than they realize.
For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.
Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.
Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.
Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.
A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.