Hepatitis C is a blood-borne virus that infects the liver, where it causes significant inflammation, damage and disruption of normal liver function. According to estimates by the World Health Organization, around 3 to 4 million people worldwide are infected with hepatitis C every year.
A study discovered that the magnitude and quality of a key immune cell’s response to two doses of the Pfizer-BioNTech COVID-19 vaccine were significantly lower in individuals with earlier SARS-CoV-2 infection compared to individuals without previous infection.
Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.
According to research, carefully formulated combinations of broadly neutralizing antibodies might effectively cure HIV while reducing the chance that the virus would evade therapy.
The dysfunction of memory CD8 + T cell can not be reverted by successful clearance of hepatitis C virus (HCV) after direct-acting antivirals (DAA) therapy, increasing the risk of reinfection with HCV.
A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.
The solutions to many of humanity's problems can be found within nature. For instance, who could have guessed that an antibiotic as powerful as penicillin would be found in a common mold, or that the drug aspirin would be derived from the bark of the willow tree?
The world knows SARS-CoV-2 intimately now, but there are more than 200 virus species capable of infecting humans and causing disease.
A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.
Hepatitis C virus thrives in humans for years, damaging the liver by causing chronic inflammation, eventually resulting in cirrhosis and liver cancer.
Scientists from the University of Basel observed in experiments with mice that cells can self-heal and eradicate viruses.
Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.
COVID-19 continues to claim lives across the world and is infecting millions more. Although several vaccines have recently become available, making significant strides towards preventing COVID-19, what about the treatment of those who already have the infection?
Hepatitis C virus (HCV) can cause chronic liver infection, which can lead to irreparable liver damage and liver cancer.
Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.
Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.
A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows.
Scientists have determined that drugs meant for treating hepatitis C can block SARS-CoV-2 main protease, which allows reproduction in the novel coronavirus.
Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections.
Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan. In order to change this unfortunate state of affairs, it is important to improve the prognosis of non-alcoholic fatty liver disease.
Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.