High throughput screening News and Research

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High-throughput screening (HTS) allows scientists to test thousands of samples at once. These samples can be of a wide variety, and include, but are not limited to, amino acids, chemical compounds or cells.

SCIEX Expands High-Throughput Screening Solutions With Echo® MS+ System

SCIEX, a global leader in life science analytical technologies, launches the Echo® MS+ system at SLAS 2024.

6 Feb 2024

Bacteria's Immune System Enhances the Effect of Antibiotics Against Cholera Pathogen

Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

22 Jan 2024

EPFL Scientists Develop Platform for Orally Available Cyclic Peptide Drugs

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

29 Dec 2023

Yeast-Based Method Could Accelerate Discovery of Plant-Based Medicinal Compounds

Cornell researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.

19 Oct 2023

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

According to new research published in Nature Biotechnology, artificial intelligence can predict on- and off-target behavior of CRISPR tools that target RNA rather than DNA.

5 Jul 2023

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

28 Apr 2023

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

The April 2023 issue of SLAS Discovery contains six full-length articles and one mini-review covering high-throughput screening (HTS) for protease-inhibiting drugs, high-content phenotypic screening and other life sciences research.

28 Apr 2023

A Nanoplasmonics Approach to Observe Real-Time Production of Cell Secretions

Researchers at the University of Geneva have developed a novel optical imaging approach that provides a four-dimensional view of cell secretions in real-time, including their spatial and temporal dynamics.

13 Apr 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

MoBIE: New user-friendly, freely available tool for sharing large imaging data sets

High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data.

24 Feb 2023

A high-throughput drug discovery assay for the endoplasmic reticulum aminopeptidase 1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

31 Jan 2023

Drug discovery method facilitates promising treatment approaches for metabolic diseases

The body’s chemical processes known as “metabolism” produce the raw materials needed for development and general health.

17 Oct 2022

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Orbit Discovery Ltd., (“Orbit”) a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, has been awarded a Smart grant by Innovate UK, the UK’s innovation agency.

From Orbit Discovery 14 Jun 2022

bit.bio launches Huntington’s disease human cell model

First neurodegenerative disease model launched from bit.bio's new ioDisease Model portfolio.

From bit.bio 10 May 2022

Dotphoton and Hamamatsu Photonics are partnering to provide the ultimate raw image compression and address the ever-growing biomedical image data volume

Dotphoton, an industry-leading raw image compression company and Hamamatsu Photonics, a world leader in optical systems and photonics manufacturing, are pleased to announce their new partnership.

From Hamamatsu Photonics Europe 26 Apr 2022

High throughput screening News and Research

SCIEX Expands High-Throughput Screening Solutions With Echo® MS+ System

Bacteria's Immune System Enhances the Effect of Antibiotics Against Cholera Pathogen

EPFL Scientists Develop Platform for Orally Available Cyclic Peptide Drugs

Yeast-Based Method Could Accelerate Discovery of Plant-Based Medicinal Compounds

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

A Nanoplasmonics Approach to Observe Real-Time Production of Cell Secretions

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

MoBIE: New user-friendly, freely available tool for sharing large imaging data sets

A high-throughput drug discovery assay for the endoplasmic reticulum aminopeptidase 1

Drug discovery method facilitates promising treatment approaches for metabolic diseases

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

bit.bio launches Huntington’s disease human cell model

Dotphoton and Hamamatsu Photonics are partnering to provide the ultimate raw image compression and address the ever-growing biomedical image data volume

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

ioSkeletal Myocytes | New product launch

New screening method allows identification of drugs that glue proteins together

Novel drug is highly effective in preventing severe COVID-19 in mice

Researchers devise a small-molecule cocktail to protect stem cells from stress

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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