High throughput screening News and Research

RSS

High-throughput screening (HTS) allows scientists to test thousands of samples at once. These samples can be of a wide variety, and include, but are not limited to, amino acids, chemical compounds or cells.

New screening method allows identification of drugs that glue proteins together

Scientists developed a new screening method that tests the effectiveness of therapeutic molecules developed to “glue” proteins together in the body.

9 Jul 2021

Novel drug is highly effective in preventing severe COVID-19 in mice

The drug diABZI -- which activates the body's innate immune response -- was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2,

31 May 2021

Researchers devise a small-molecule cocktail to protect stem cells from stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

29 Apr 2021

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

New high-throughput system for testing drug candidates to treat neurodegenerative diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

19 Mar 2021

New approach could speed the search for promising therapies

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

Research team to develop new method for high throughput drug screening

Nuclear magnetic resonance (NMR) is an important tool in drug research, since it can quantify and spatially resolve binding of drugs to pathogens. So far, however, NMR has lacked the sensitivity and throughput to scan large libraries of drug candidates.

10 Nov 2020

Researchers discover a new mechanism to regulate nerve impulses

Researchers at Linköping University, Sweden, have discovered a new mechanism by which substances can open a certain type of ion channel and in this way regulate nerve impulses.

13 Oct 2020

Quality of lab procedures has a big impact on discovery of effective drugs

In their quest to find new drugs to treat deadly diseases, scientists study millions of molecules at high speed at the same time. Often it is enzymes that are investigated as targets in these 'high-throughput' screenings.

22 Jul 2020

Scientists discover new antiviral drug against paramyxovirus

A new antiviral drug that is effective against a broad range of human pathogens in the paramyxovirus family, such as the human parainfluenzaviruses and measles virus, has been discovered by researchers in the Institute for Biomedical Sciences at Georgia State University.

14 Jul 2020