The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.
Scientists have observed for the first time what it looks like in the key memory region of the brain when a mistake is made during a memory trial.
In a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for why the area, commonly referred to as 'the brain's memory center', is vulnerable to damage and degeneration, a precursor to Alzheimer's disease.
The pivotal role played by the APP protein in Alzheimer’s disease is well known.
A research team has revealed that neural stem cells (NSCs)—that is, the stem cells of the nervous system—age quickly.
A genetic engineering approach has helped scientists to drastically decrease the levels of tau protein.
AZoLifeSciences speaks to researchers from Tianjin Medical University about their latest research that led to the discovery of two new genes that are linked to Alzheimer's disease.
Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.
Coffee, cola, or an energy drink: caffeine is the world's most widely consumed psychoactive substance. Researchers from the University of Basel have now shown in a study that regular caffeine intake can change the gray matter of the brain. However, the effect appears to be temporary.
Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away.
On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery.
It's a fact of life that things break down. And when they do, whether it's your car, the roof, or a blocked artery, there are people who we can call to help with the repairs.
Scientists have identified a novel mechanism that is responsible for causing the abnormal development of neuronal connections in the mice brain.
Alzheimer's disease is one of the most serious diseases in an aging society, yet the cause is often unclear and there is no appropriate treatment method.
Adopting a third-person, observer point of view when recalling your past activates different parts of your brain than recalling a memory seen through your own eyes, according to a new paper.
A hospital nurse for 33 years, Nanette Miller would call her husband Frank at the end of each shift to let him know she was coming home.
The hippocampus is a region within the brain that contains many neurons that help us to navigate in space. This leads to the nickname of this area: the GPS of the brain.
Studies on cellular dynamics are vital to interpret the development of cells and the progression of various diseases.
Among the many things rodents have taught neuroscientists is that in a region called the hippocampus, the brain creates a new map for every unique spatial context - for instance, a different room or maze.
Primary cilia are structures that act like antennas for cells to identify signals and occur less in mice affected by Fragile X syndrome since birth.
The ability of the human brain to process and store information is determined to a large extent by the connectivity between nerve cells. Chemical synapses are very important in this context as they constitute the interface for the transmission of information between individual nerve cells.