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New insight into human genome evolution

Researchers discovered that in one out of every 4,000 births, some of the genetic code from the mitochondria—the “batteries” that power human cells—inserts itself into the DNA, giving a startling new insight into how humans evolve.

6 Oct 2022

Novel molecules alleviate pain, avoid sedating effect

According to new research headed by UC San Francisco scientists, a newly found group of molecules relieved pain in mice whilst preventing the sedating effect that limits the usage of opiates.

3 Oct 2022

New role for huntingtin protein—neuronal regeneration

A recent study led by the University at Buffalo proposes a novel role for the huntingtin protein (HTT), which leads to Huntington’s disease when mutated.

28 Sep 2022

An inventory of human genetic variation through upgrading the 1000 genomes project resource

The first large-scale WGS project to produce a catalog of human genetic variation was the 1000 Genomes Project (1kGP), which was released as an open-access resource seven years ago.

8 Sep 2022

Simple blood test helps identify patients developing neurotoxic side effects

The treatment of various tumors has been transformed by cell-based immunotherapy, often known as CAR-T cell therapy. To target and combat specific forms of leukemia and lymphoma, the treatment employs genetically engineered T cells.

8 Sep 2022

A “stress test” with a previously unknown gene to revive the exhausted T cells

The task of battling cancer cells can fatigue T cells employed in immunotherapy treatments, or they could shut down once they penetrate tumors. Researchers at the Gladstone Institutes and UC San Francisco have strengthened the therapeutic cells’ resistance via a CRISPR-based edit on their genomes.

30 Aug 2022

BIDMC researchers develop a transformative approach to make more of beige adipose tissues

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

18 Aug 2022

RASTRUM™ - the 3D Printer of Living Cells, Honored in Annual Awards by Leading Business Magazine

RASTRUM™ has taken out the top prize in the Experimental category. RASTRUM™ prints human cells into living tissue models to supercharge research into cancer and other diseases using revolutionary drop-on-demand technology.

From Inventia Life Science 16 Aug 2022

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Inventia Life Science, a leader in automated generation of complex 3D cell models, and PhenoVista Biosciences, a top provider of custom imaging-based phenotypic assay services, have entered into a partnership to deliver high-content cell-based assay services for drug discovery.

From Inventia Life Science 16 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Researchers identify key molecular differences between initial and metastatic tumors

Researchers at Johns Hopkins Medicine claim to have discovered significant molecular variations between cancer cells that adhere to an initial tumor and those that spread out to develop distant tumors while researching the fatal form of breast cancer known as triple negative.

9 Aug 2022

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

An antibody that is successfully used to treat a variety of tumors has been replaced with a tiny molecule that researchers from Tel Aviv University and the University of Lisbon have jointly found and manufactured.

9 Aug 2022

Study proposes a systematic engineering approach of optimizing protein-fortified food inks

As the global population continues to age and grow, the demand for protein-rich food is also expected to increase concurrently.

8 Aug 2022

Researchers create CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells taken from the patient’s own blood are modified to contain so-called chimeric antigen receptors (CAR), which provide the T cells the ability to target and eradicate tumor cells.

8 Aug 2022

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

Rady Children’s Institute for Genomic Medicine (RCIGM®) recently announced the publication in Nature Communications of research that describes and examines the efficiency of Genome-to-Treatment (GTRxTM), a computer-controlled, virtual disease management system that combines a quick Whole Genome Sequencing (rWGS®) diagnosis accomplished in 13.5 hours with a custom lab management information system and analysis pipeline.

28 Jul 2022

Research shows how protein deficiency creates motor disorders in flies

Scientists at the Universities of Bonn and Osnabrück have identified a protein that when defective in flies results in motor dysfunction.

26 Jul 2022

Study highlights retrotransposition in CRISPR gene therapy clinical trials

Worldwide clinical studies for gene therapy utilizing CRISPR/Cas9 gene editing are now underway for a number of disorders. A study from Boston Children’s Hospital that was released in Nature Communications on June 27th, 2022, alerts readers to a possible CRISPR editing risk that has not yet been identified.

8 Jul 2022

Probiotics do not enhance unhealthy vaginal health, recent study shows

Several factors, such as the type of bacteria that naturally colonize the reproductive tract, can influence pregnancy chances in IVF. “Good” bacteria in the form of probiotics are gaining popularity in the treatment of vaginal microbiota imbalances in women.

5 Jul 2022

Study deciphers the mechanisms of bacterial host cell adhesion

To create a new class of antibiotics, investigators from University Hospital Frankfurt and Goethe University Frankfurt have figured out how bacteria adhere to host cells.

4 Jul 2022

Research highlights the new genetic variations and pediatric NAFLD severity

A multidisciplinary group of researchers at the University of California San Diego School of Medicine have advanced investigations into the genetic causes of NAFLD in children.

1 Jul 2022