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Cryobioprinting; A New Bioprinting Technique

In this interview, we speak to Dr. Y. Shrike Zhang about his latest bioprinting technique that allows tissues to be preserved for later use.

From Harvard Medical School 4 Feb 2022

MIT researchers develop new way to deliver RNA in a capsule

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

1 Feb 2022

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Analysis of the entire tumor RNA picks up more clinically relevant genetic changes in children with cancer than traditional diagnostic methods, new research has shown.

28 Jan 2022

Researchers develop a high-throughput test to detect DNA repair factors

The DNA in every human cell is subjected to thousands of insults and injuries on a daily basis.

21 Jan 2022

Memory T cells formed after prior infection or vaccination respond to omicron variant

The omicron variant can partly evade the antibody response provided by vaccination or infection with previous variants of SARS-CoV-2.

20 Jan 2022

Study identifies respiratory syncytial viral protein that mediates RSV-induced autophagy

A viral protein might contain information that could be used to avoid pneumonia due to the body’s overactive response to respiratory viruses, such as COVID-19.

20 Jan 2022

Researchers discover a gene variant that protects against severe COVID-19 infection

An international metastudy led by researchers at Karolinska Institute in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

17 Jan 2022

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Changes in the activity of gene networks may explain arteriosclerosis risk

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

13 Jan 2022

Researchers conduct genome sequencing studies in children with in-born immunity disorders

The Sanford Children’s Genomic Medicine Consortium has ten hospitals collaborating for whole genome sequencing studies on patients with suspected inborn immunity disorders (IEI).

13 Jan 2022

Researchers map the cellular landscape in diabetic foot ulcers

Diabetic foot ulcerations – open sores or wounds that refuse to heal – are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone.

11 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

The Omicron variant was detected for the first time in South Africa in November 2021 and has since spread to many countries.

From Institut Pasteur 10 Jan 2022

CAR T cells produced in vivo using modified mRNA treat cardiac injury

A new study by researchers from the University of Pennsylvania shows that experimental immunotherapy can temporarily reprogram the immune cells of patients.

10 Jan 2022

Experts introduce new gene therapy approach for muscle weakness

Experts at Children’s National Hospital have created a new pre-clinical gene therapy for the rare condition limb-girdle muscular dystrophy (LGMD) 2B.

7 Jan 2022

Novel delivery system for genome editing in vascular endothelial cells developed

The laboratory of Youyang Zhao developed a novel nanoparticle to deliver genome editing technology, such as CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

7 Jan 2022

New model system reveals how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

A new technique takes bioprinting -; in which an ink of cells is printed, layer by layer, to form a structure -; to a whole new, and icy level. Investigators from the Zhang lab at Brigham and Women's Hospital have developed a technology that they term "cryobioprinting," a method that uses a bioink embedded with cells to print frozen, complex structures that can be easily stored for later use.

31 Dec 2021

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

Severe injuries to the lung from diseases such as COVID-19 trigger abnormal stem cell repair that alters the architecture of the lung. The aberrant stem cell differentiation in response to injury can prevent the restoration of normal lung function.

31 Dec 2021

Hospital News and Research

Cryobioprinting; A New Bioprinting Technique

MIT researchers develop new way to deliver RNA in a capsule

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Researchers develop a high-throughput test to detect DNA repair factors

Memory T cells formed after prior infection or vaccination respond to omicron variant

Study identifies respiratory syncytial viral protein that mediates RSV-induced autophagy

Researchers discover a gene variant that protects against severe COVID-19 infection

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Changes in the activity of gene networks may explain arteriosclerosis risk

Researchers conduct genome sequencing studies in children with in-born immunity disorders

Researchers map the cellular landscape in diabetic foot ulcers

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

CAR T cells produced in vivo using modified mRNA treat cardiac injury

Experts introduce new gene therapy approach for muscle weakness

Novel delivery system for genome editing in vascular endothelial cells developed

New model system reveals how tiny bacteria from the environment have adapted to live inside humans

Olfactory receptor gene may drive breast cancer metastasis to the brain

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

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