Hypoxia News and Research

RSS

Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Reinvigorating T Cells Offers Hope for More Effective Cancer Immunotherapy

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

8 Jul 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

How RNA-Binding Proteins and Circular RNAs Shape Tumor Biology

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

13 May 2025

Placenta-Derived Signals Improve Liver Organoid Size and Function

Organoids, which are designed to mimic human organs, hold promise for both research and treatment;

9 Apr 2025

Researchers Discover Genetic Markers for PFAS-Induced Neurotoxicity

Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain.

7 Jan 2025

Study Reveals Mechanism Behind T Cells' Cancer-Killing Power in Hypoxia

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective.

16 Dec 2024

Comprehensive Review of Intracellular Checkpoints in NK Cell Biology and Cancer

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their presence in tumors correlates with improved patient outcomes in a variety of cancers.

29 Nov 2024

3D Tumor Microenvironment Model Highlights Role of Ischemia and Acidification in Cancer Spread

Developed 3MIC model simulates tumor microenvironments, enabling direct observation of ischemic effects on cancer cell invasiveness and drug resistance.

4 Nov 2024

Chloroplast-Infused Cells Revolutionize Tissue Engineering

Recent research from Japan has demonstrated that chloroplasts from algae can be integrated into hamster cells, allowing these cells to perform photosynthesis.

1 Nov 2024

New Study Sheds Light on Genetic Adaptations of Papua New Guinean Populations

Papua New Guinea (PNG) has a wide range of environments, each presenting unique challenges to human survival. Highlanders and lowlanders of PNG are striking examples of populations facing distinct environmental stress.

2 May 2024

FluidForm Bio 3D Bioprints Human Cardiac Tissue for Drug Development Breakthrough

FluidForm Bio, a leader in developing life-like human tissue to treat disease, shares recent advancements in building human cardiac tissues using FRESH 3D bioprinting.

13 Dec 2023

Unraveling Oxygen's Impact on Protein Dynamics

Understanding the adverse effects of insufficient oxygen becomes apparent with the simple act of holding ones breath for too long.

11 Dec 2023

Where Does the Light Come From? Optical Properties Allow Plants to “See” Light

An innovative study led by Professor Christian Fankhauser at UNIL and colleagues at EPFL has combined expertise in biology and engineering to reveal that a light-sensitive plant tissue uses the optical properties of the air-water interface to create a light gradient that is ‘visible’ to the plant.

24 Nov 2023