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Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Mice study explains why humans expressing CHT gene variant exhibit attentional vulnerabilities

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

8 Apr 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

New technique for better visualizing the CNS fibroblasts

The central nervous system (CNS) consists of several types of cells having varied specialized functions.

7 Apr 2022

Researchers discover 15 genetic 'hotspots' that speed up or slow down brain aging

Researchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow it down -; a finding that could provide new drug targets to resist Alzheimer's disease and other degenerative brain disorders, as well as developmental delays.

6 Apr 2022

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.

6 Apr 2022

Plant biologists determine molecular ‘blueprint’, showing how plants observe light

For survival, plants depend on their ability to detect light. Plants, unlike animals, do not have photoreceptors in their eyes to receive and transmit messages from visual inputs.

1 Apr 2022

AI and robotics identify new cellular hallmarks of Parkinson's disease

A study published today in Nature Communications unveils a new platform for discovering cellular signatures of disease that integrates robotic systems for studying patient cells with artificial intelligence methods for image analysis.

28 Mar 2022

Novel protein Atossa regulates cell invasion

Researchers from the Institute of Science and Technology Austria have found a novel protein that stimulates energy generation inside immune cells, allowing them to penetrate more effectively.

24 Mar 2022

Bacteria form distinctive lane-like patterns when constrained to a channel

It's well understood that populations of species don't distribute at random. Rather, as populations grow, individuals are organized around barriers in the landscape.

22 Mar 2022

Specific brain cells in the claustrum of mice control stress-induced anxiety behaviors

It is well known that long-term exposure to stress can lead to serious psychiatric problems. However, the precise mechanisms underpinning the stress response have remained largely elusive.

From Osaka University 21 Mar 2022

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Researchers have created a novel method that allows them to correlate particular genes to complex tumor properties at a size and resolution that has never been achievable.

21 Mar 2022

Increased pressure triggers sudden 'cell burst' in 3D tumor model

Biological processes such as wound healing and cancer cell invasion rely on the collective and coordinated motion of living cells.

17 Mar 2022

Researchers conduct a detailed study of skin layer, likely to assist in new products and treatments

Scientists have precisely studied the skin’s resistant barrier layer, producing the most thorough molecular map of its form to aid in the creation of novel skin products and treatments.

16 Mar 2022

Sustainable Food Packaging that Protects Food from Microbes

In this interview, AZoLifeSciences talks to Dr. Mary Chan about the development of a new ‘smart’ food packaging that is biodegradable and has antimicrobial properties, extending the shelf-life of fresh food.

From Nanyang Technological University Singapore (NTU Singapore) 15 Mar 2022

Cellular therapy leads to meaningful functional improvements in DMD patients

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

From The University of California, Davis 14 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022