Immune System News and Research

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Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

New gene editing tool helps analyze the mysterious quirk of bacteria

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations.

3 May 2021

Shortage of DNA building blocks triggers inflammation

Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell.

3 May 2021

Researchers identify specific proteins that play a key role in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease.

3 May 2021

Processed diet reduces gut bacteria and promotes encroachment of microbiota into the intestine

Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Apr 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

Researchers have discovered a possible connection between increased vulnerability to COVID-19 infection and exposure to organophosphate pesticides.

27 Apr 2021

SDIR1 enzyme plays a major role in the expression of defense gene in plants

A new study offers evidence that microbes are trying to hijack the plant immune system to induce disease while also offering insights into a new mechanism.

26 Apr 2021

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

A new study has shown that it is viable to reduce tumor growth by a therapy that involves tagging cancer cells with various therapeutic molecules.

26 Apr 2021

New AI model predicts targets for previously unmapped T cells against coronavirus

A research team has created an AI technique that can bind immune cells to their targets and uncouple the types of white blood cells that identify SARS-CoV-2.

26 Apr 2021

Macrophages perform necessary damage-control function following tissue injury

Cardiovascular disease, the most common cause of death, is the result of oxygen deprivation as blood perfusion to affected tissue is prevented. To halt the development of the disease and to promote healing, re-establishment of blood flow is crucial.

26 Apr 2021

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

Small molecular changes can have dramatic impact on the CAR T cell function

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't respond, they went back to the drawing board to determine why.

23 Apr 2021

Study offers new ways to think about the immune system

Scientists have discovered new methods to interpret the immune system, as part of a new study reported in the Nature journal.

21 Apr 2021

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Antibodies may not inhibit SARS-CoV-2 variants from minks

It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals. Mutations were acquired in the spike protein, which is crucial for the entry of the virus into host cells and represents the central point of attack for antibodies.

20 Apr 2021

New breakthrough in understanding the role of high-risk immune genes in rheumatoid arthritis

Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA).

19 Apr 2021

New CRISPR technology allows scientists to switch off any gene in human cells

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

19 Apr 2021

Ebola virus protein changes shape by using human RNA

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the protein's destined function. Tens of thousands of singular shapes drive the tens of thousands of needed functions.

15 Apr 2021

Scientists discover how immune response to TB differs in adults and newborn babies

The immune response to tuberculosis (TB) differs in adults and newborn babies due to the way immune cells use energy to kick into gear in a bid to kill the bacteria. This fresh discovery - just published in leading journal, Frontiers in Immunology - offers hope for improving treatments for what remains a deadly disease.

15 Apr 2021

Immune System News and Research

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

New gene editing tool helps analyze the mysterious quirk of bacteria

Shortage of DNA building blocks triggers inflammation

Researchers identify specific proteins that play a key role in the development of dendritic cells

Processed diet reduces gut bacteria and promotes encroachment of microbiota into the intestine

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

SDIR1 enzyme plays a major role in the expression of defense gene in plants

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

New AI model predicts targets for previously unmapped T cells against coronavirus

Macrophages perform necessary damage-control function following tissue injury

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Small molecular changes can have dramatic impact on the CAR T cell function

Study offers new ways to think about the immune system

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

Antibodies may not inhibit SARS-CoV-2 variants from minks

New breakthrough in understanding the role of high-risk immune genes in rheumatoid arthritis

New CRISPR technology allows scientists to switch off any gene in human cells

Ebola virus protein changes shape by using human RNA

Scientists discover how immune response to TB differs in adults and newborn babies

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