Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Study may help develop multi-pronged HIV eradication strategies

A team of researchers from the University of California - Davis Health (UC Davis) has made a breakthrough discovery of a unique type of stem cell that reduces the amount of the virus that causes AIDS.

25 Jun 2021

Novel device can help treat type I diabetes mellitus

Type I Diabetes Mellitus, also called T1D, is an autoimmune disorder that results in an irreversible loss of insulin-producing beta-cells found in the pancreas.

2 Apr 2021

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

A new study indicates that protein kinases, which initiate the process that erodes the body’s immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.

2 Mar 2021

New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells.

10 Feb 2021

Severe genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

2 Feb 2021

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

23 Dec 2020

Scientists successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Chemists identify effective inhibitors to block the uptake of SARS-CoV-2

The cell membrane is impermeable to viruses: to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes.

23 Nov 2020

Endogenous viral elements play important role in genome evolution of green algae

Viruses are tiny invaders that cause a wide range of diseases, from rabies to tomato spotted wilt virus and, most recently, COVID-19 in humans. But viruses can do more than elicit sickness -- and not all viruses are tiny.

19 Nov 2020

Discovering a new step in immune cell generation

In this interview, Dr. Shalin Naik speaks to AZoLifeSciences about his team's latest research that led to the discovery of a new step in the development of T and B cells that could help us to better understand leukemia.

12 Nov 2020

Study probes mechanism by which COVID-19 distribution in the body damages erythrocytes

Experts have investigated the mechanisms of COVID-19 inside-the-body distribution related to the damage of erythrocytes.

2 Nov 2020

Study shows antibody levels drop rapidly in recovering COVID-19 patients

The lack of effective treatments for COVID-19 is forcing hospitals to use blood plasma from recovering patients to treat those who have severe symptoms.

19 Oct 2020

Rare gene mutation eliminates immune cell population

A study has allowed researchers to identify a rare human gene mutation that removes a population of immune cells, called mucosal-associated invariant T cells.

27 Jul 2020

Research identifies TLR7 gene that predisposes individuals to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

27 Jul 2020

New tools developed to test the ability of antibodies to neutralize SARS-CoV-2

Researchers at The Rockefeller University in New York have developed new tools to rapidly test the ability of antibodies to neutralize SARS-CoV-2, the novel coronavirus responsible for the COVID-19 pandemic.

22 Jul 2020

Study shows how T cells become cancer-killing cells

Within the immune system, the T lymphocytes operate to kill cancer cells or infected cells.

21 Jul 2020

New method reveals the dynamics of HIV Gag-protein lattice structure

Viruses are scary. They invade our cells like invisible armies, and each type brings its own strategy of attack. While viruses devastate communities of humans and animals, scientists scramble to fight back.

17 Jul 2020

Whole genome sequencing can improve rare disease diagnosis

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

25 Jun 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

New study shows how a protein works as 'master regulator' in the immune system

Scientists at the La Jolla Institute for Immunology have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases.

22 Jun 2020