Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.
Type I Diabetes Mellitus, also called T1D, is an autoimmune disorder that results in an irreversible loss of insulin-producing beta-cells found in the pancreas.
A new study indicates that protein kinases, which initiate the process that erodes the body’s immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.
Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells.
Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.
Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.
Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.
The cell membrane is impermeable to viruses: to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes.
Viruses are tiny invaders that cause a wide range of diseases, from rabies to tomato spotted wilt virus and, most recently, COVID-19 in humans. But viruses can do more than elicit sickness -- and not all viruses are tiny.
In this interview, Dr. Shalin Naik speaks to AZoLifeSciences about his team's latest research that led to the discovery of a new step in the development of T and B cells that could help us to better understand leukemia.
Experts have investigated the mechanisms of COVID-19 inside-the-body distribution related to the damage of erythrocytes.
The lack of effective treatments for COVID-19 is forcing hospitals to use blood plasma from recovering patients to treat those who have severe symptoms.
A study has allowed researchers to identify a rare human gene mutation that removes a population of immune cells, called mucosal-associated invariant T cells.
Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.
Researchers at The Rockefeller University in New York have developed new tools to rapidly test the ability of antibodies to neutralize SARS-CoV-2, the novel coronavirus responsible for the COVID-19 pandemic.
Within the immune system, the T lymphocytes operate to kill cancer cells or infected cells.
Viruses are scary. They invade our cells like invisible armies, and each type brings its own strategy of attack. While viruses devastate communities of humans and animals, scientists scramble to fight back.
A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.
AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.
Scientists at the La Jolla Institute for Immunology have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases.
Viruses are ever-present pathogens that lead to severe infectious diseases in humans as well as in agricultural crops.