Inflammatory Bowel Disease News and Research

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Inflammatory bowel disease (IBD) is an ongoing or chronic health problem that causes inflammation and swelling in the digestive tract. The irritation causes bleeding sores called ulcers to form along the digestive tract. This in turn can cause crampy, abdominal pain and severe bloody diarrhea.

Food dyes may cause disease when the immune system is dysregulated

Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report.

14 May 2021

Processed diet reduces gut bacteria and promotes encroachment of microbiota into the intestine

Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Apr 2021

Study reveals the evolution of the human gut microbiota

The gut microbiota in human beings mostly evolves into an adult-like composition five years after birth, but significant differences continue to persist.

1 Apr 2021

Components of Neanderthals' gut microbiota are essential for human health

Neanderthals' gut microbiota already included some beneficial micro-organisms that are also found in our own intestine.

5 Feb 2021

New model can help identify potential drug targets for ulcerative colitis

Scientists from the Lerner Research Institute at Cleveland Clinic have designed an innovative, patient-derived model of ulcerative colitis that will help scale up studies into new therapies for chronic inflammatory bowel disease.

12 Jan 2021

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

22 Dec 2020

Study: DOT1L enzyme is essential for humoral immune responses

Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists.

17 Dec 2020

New genetic associations predict susceptibility to Takayasu arteritis

A team of international collaborators, headed by scientists from the University of Pittsburgh School of Medicine, have detected novel genetic associations that can estimate the susceptibility of individuals to Takayasu arteritis—a rare inflammatory disease.

14 Dec 2020

Specific cellular pathways in the fetal gut may reactivate Crohn’s Disease

Researchers have successfully monitored the initial stages of gut development in a human fetus, in explicit detail.

8 Dec 2020

Study suggests that melatonin may be a viable treatment option for COVID-19

New findings indicate that melatonin could be a potential treatment option for COVID-19.

10 Nov 2020

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

30 Oct 2020

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Severe ulcerative colitis - a form of inflammatory bowel disease (IBD) - has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found.

30 Oct 2020

Cell therapy designed to treat inflammatory bowel disease

The results obtained are encouraging and the researchers could make headway in a multifunctional cell therapy system to treat inflammatory bowel disease.

29 Sep 2020

Polyphenolic compound extracted from blueberry can treat inflammatory bowel disease

Different plants and their products contain “bioactive” components that can reduce human diseases.

25 Sep 2020

Neuronal connections that trigger insomnia linked to stress-induced changes in the immune system

Scientists at Cold Spring Harbor Laboratory and Stanford University have pinpointed the circuit in the brain that is responsible for sleepless nights in times of stress--and it turns out that circuit does more than make you toss and turn.

10 Sep 2020

New cellular pathway can protect cells from infection by Ebola virus, coronavirus

Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2.

28 Aug 2020