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Study proposes methods to purge unstable regulatory T cells

Scientists from the Babraham Institute, United Kingdom and VIB-KU Leuven, Belgium, came up with two solutions that can overcome a major clinical limitation of immune cell therapies. The researchers chose mice as their model. The findings were published recently in the journal Science Immunology.

27 Jul 2021

New technique can edit plant chloroplasts without leaving any heritable changes

Geneticists at the University of Tokyo have developed a new gene-editing technique that modifies the chloroplast of plant cells.

2 Jul 2021

Study shows how different organisms can prevent deadly DNA damage during evolution

Researchers from the University of Bergen discovered how species ranging from crops to corals can prevent harmful DNA damage during evolution.

26 Apr 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

From UC San Diego 19 Feb 2021

Cancer cells can exchange and recombine their genetic material, shows study

Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes.

22 Jan 2021

New study explores the role of genetics in prostate cancer

When compared to other groups, certain ethnic and racial groups tend to suffer more often, and fare worse, from common ailments.

5 Jan 2021

Statins can reduce risk of heart attacks and other cardiovascular diseases

According to a study recently published in the eLife journal, cholesterol-lowering drugs, known as statins, may lower cancer risk in humans via a pathway unassociated with cholesterol.

15 Oct 2020

'Survival of the fittest': How meiotic drivers shape the evolution of gamete formation

It can be hard to dispute the common adage 'survival of the fittest'. After all, "most of the genes in the genome are there because they're doing something good," says Sarah Zanders, PhD, assistant investigator at the Stowers Institute for Medical Research

18 Aug 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020

Researchers use mathematical modeling to unravel the mechanisms behind tetraploidy

Cell division is a fundamental process that organisms need to reproduce, grow, and make repairs. But when an error disrupts this complex biological process, cellular abnormalities can lead to diseases, such as cancer, where cells are enabled to grow and divide out of control.

27 Jul 2020

Researchers identify how certain gene mutations cause ALS

Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

11 Jun 2020