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Yale researchers uncover mechanism driving Wolfram Syndrome

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment.

20 Jul 2020

A new approach to combat drug resistance in aggressive age-related macular degeneration

An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration, the leading cause of irreversible blindness in the elderly.

17 Jul 2020

Study shows the negative impacts of cannabis use

Constant exposure to cannabis could have an adverse effect on sociability. According to studies, in certain indviduals, such exposures may result in reduced social interactions and withdrawal symptoms.

13 Jul 2020

Study identifies a new target for cancer treatment

Planar cell polarity (PCP) is a kind of process where polarization of the epithelial tissues occurs inside the plane of the epithelium. This process plays a significant role in the development and function of organs.

13 Jul 2020

Study: PINK1 and Parkin work together to induce selective autophagy

Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria to induce selective autophagy called mitophagy.

10 Jul 2020

Study shows how motor proteins function in their native crowded cell environments

Several diseases, including neurodegenerative disorders, have been associated with the defective functioning of motor proteins involved in cell transport.

From New York University (NYU) 7 Jul 2020

Anammox bacteria show ability to 'breathe' solid-state matter

A type of anaerobic bacteria responsible for more than 50 percent of nitrogen loss from marine environments has been shown to use solid-state matter present outside their cells for respiration.

30 Jun 2020

How upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Scientists study how cancer cells in the liver react to magnetic nanoparticles

Scientists from the Immanuel Kant Baltic Federal University and National University of Science and Technology "MISiS" have studied how magnet nanoparticles affect cancer cells in the human liver.

26 Jun 2020

Simplified artificial cell sheds light on the dynamics of cellular symmetry

Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry.

26 Jun 2020

Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

Researchers discover new mechanism which may stimulate blood vessels' inner liner

Blood vessels are the body's transportation system, carrying oxygen and nutrients to cells and whisking away waste.

15 Jun 2020

New protein design could help in drug discovery for Parkinson’s disease

The neurotransmitter dopamine plays a vital role in everything, starting from motor control to higher cognitive functions, arousal, motivation, sexual gratification, and reinforcement.

12 Jun 2020

Baylor researchers uncover a novel mechanism that triggers cellular immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that specifically recognize parts of the invading microbe and mediate its destruction.

12 Jun 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Protein dynamics can help fight bacterial infections

When pathogenic bacteria infect, the body’s immune system attempts to remove these invaders. One method to do this is to trigger an inflammatory response.

10 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Study identifies key protein required for optimal immune responses to cancer

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Solove Research Institute has identified a protein within certain immune cells that is required for optimal immune responses to cancer.

3 Jun 2020

Researchers create 3D fluorescence and phase imaging of living cells based on digital holography

A research group led by Kobe University's Professor MATOBA Osamu (Organization for Advanced and Integrated Research) has successfully created 3D fluorescence and phase imaging of living cells based on digital holography.

2 Jun 2020

Research suggests new possibility for how glucose transporters operate

Some of the most essential processes on the planet involves water and energy entering and leaving cells.