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Study discusses the role of insects as a potential new food allergen

Those with food allergies must avoid allergens in food. Health problems can be triggered by even the smallest traces for those affected. This is why manufacturers of ready-made foods must list the ingredients on the packaging.

21 Oct 2020

New tool can provide non-invasive decision support for treating lung cancer

Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related death worldwide, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors.

19 Oct 2020

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib.

7 Oct 2020

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020

Researchers identify new way to treat chronic myelogenous leukemia

Scientists have detected a second path to treat chronic myelogenous leukemia, which is known to affect older adults, despite its resistance to drugs.

22 Sep 2020

An efficient therapeutic strategy against KRAS mutant lung tumors in mice

The KRAS oncogene is involved in at least one fifth of all human cancers: KRAS mutations are directly responsible for 32% of lung tumors and 96% of pancreatic tumors.

10 Sep 2020

Study highlights the role of brain astrocyte cells in Parkinson's disease pathology

A new study using induced pluripotent stem cell (iPSC) technology links astrocyte dysfunction to Parkinson's disease (PD) pathology.

9 Sep 2020

Study shows chameleon-like protein can alter human brain

Neurons contain a chameleon-like protein that can alter its mind and, during the process, modifies the human brain.

26 Aug 2020

New approach could slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

25 Aug 2020

Study shows how FAK protein is activated on lipid membranes

A team of researchers has recently described the mechanistic details regarding the activation of the Focal Adhesion Kinase (FAK) on lipid membranes.

12 Aug 2020

Mitochondrial reprogramming may offer new treatment strategies against breast cancer

A study performed has revealed that oxygen-deprived breast cancer cells transmit messages that cause oncogenic modifications in the surrounding healthy cells.

11 Aug 2020

Study indicates a powerful treatment for pulmonary fibrosis

A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF).

7 Aug 2020

Discovery Shows Promise For Treating Huntington's Disease

Huntington disease is a progressive debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition.

6 Aug 2020

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

29 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Study shows how T cells become cancer-killing cells

Within the immune system, the T lymphocytes operate to kill cancer cells or infected cells.

21 Jul 2020

Scientists gain insights into how parasitic bacterium gives rise to lesions

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis." Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans.

17 Jul 2020