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Study identifies genes and molecular pathways most sensitive to chemical exposures

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

Dual-chip system for monitoring heart toxicity from breast cancer drugs

Breast cancer is the most commonly occurring cancer for women around the world, and much effort has been spent in the development of therapies to treat this disease.

27 Oct 2020

Ketogenic diets can prevent or reverse heart failure caused by metabolic process

Research from Saint Louis University finds that high fat or "ketogenic" diets could completely prevent, or even reverse heart failure caused by a metabolic process.

27 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

Researchers assign immunological memory function to cytotoxic natural killer cells

A new study by researchers from the Medical University of Vienna could prove beneficial for the human immune system.

21 Oct 2020

New strategy for capturing interactions among glycans and protein activators in live cells

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Researchers discover new protocol to detect lipid production in microalgae

Dietary supplementation of fatty acids produced from microalgae have wide-reaching health benefits for humans, including the ability to reduce obesity, diabetes and fatty liver disease, preventing hair loss, and assisting wounds to heal.

16 Oct 2020

Lymphocytes play crucial role in controlling virus shedding in asymptomatic COVID-19 patients

COVID-19 remains stubbornly inconsistent. More than a million people have died and 35 million have been diagnosed, but a large fraction of people infected with the coronavirus--about 45%, according to recent estimates--show no symptoms at all.

15 Oct 2020

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Volume 11, Issue 28 of Oncotarget features "Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation" by Gaba et, al. which reported that reliable development of Oncopig HCC cell lines was demonstrated through hepatocyte isolation and Cre recombinase exposure across 15 Oncopigs.

12 Oct 2020

Maternal high sugar diet can impact developmental outcomes in infants

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease. New research shows that when consumed by moms during the breastfeeding period, a high sugar diet can also impact developmental outcomes during infancy.

7 Oct 2020

Deep learning-based technique could boost drug development

When you take a medication, you want to know precisely what it does. Pharmaceutical companies go through extensive testing to ensure that you do.

6 Oct 2020

MIT engineers develop a method to turn off specific genes in bone marrow cells

Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells.

From Massachusetts Institute of Technology (MIT) 6 Oct 2020

Study unravels how immunotherapy is 'uniquely suppressed' by liver cancers

Though cancer immunotherapy has become a promising standard-of-care treatment--and in some cases, perhaps a cure--for a wide variety of different cancers, it doesn't work for everyone, and researchers have increasingly turned their attention to understanding why.

5 Oct 2020

Liver News and Research

Study identifies genes and molecular pathways most sensitive to chemical exposures

Dual-chip system for monitoring heart toxicity from breast cancer drugs

Ketogenic diets can prevent or reverse heart failure caused by metabolic process

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

Researchers assign immunological memory function to cytotoxic natural killer cells

New strategy for capturing interactions among glycans and protein activators in live cells

Researchers discover new protocol to detect lipid production in microalgae

Lymphocytes play crucial role in controlling virus shedding in asymptomatic COVID-19 patients

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Maternal high sugar diet can impact developmental outcomes in infants

Deep learning-based technique could boost drug development

MIT engineers develop a method to turn off specific genes in bone marrow cells

Study unravels how immunotherapy is 'uniquely suppressed' by liver cancers

Type and direction of force on a cell can alter gene expression

Researchers use multiple techniques to understand the effect of aging in humans

Identifying genetic factors that mitigate the risk of diabetes

Developing computational algorithms to enable a closer look at the 3D genome

New study can help develop diagnostic markers for type 2 diabetes

New study reveals metabolic signature of SARS-CoV-2 infection involving signs of multi-organ damage

Study sheds new light on the evolution of gene expression patterns

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