Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases
Cells work around the clock to deliver, maintain, and control every aspect of life. And just as with humans, communication is a key to their success.
Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.
In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report.
In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.
A group of researchers from the University of Toronto have developed a credit-card sized tool for growing cancer cells outside the human body, which they believe will enhance their understanding of breast cancer metastasis.
Planar cell polarity (PCP) is a kind of process where polarization of the epithelial tissues occurs inside the plane of the epithelium. This process plays a significant role in the development and function of organs.
Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.
Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.
Fluorescent tagging is a powerful way of analyzing communications between cells. This method enables the analysis of numerous cell populations.
Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in the poor prognosis of cancer patients.
Research led by Queen Mary University of London has revealed novel insights into the molecular circuitry controlling cancer cell growth and spread. The findings highlight new pathways involved in these key processes of cancer progression that may represent targets for therapies.
A novel molecule LIH383 developed by scientists at the Luxembourg Institute of Health binds to and inhibits a formerly unknown opioid receptor in the brain.
Johns Hopkins Kimmel Cancer Center researchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified a lipid-regulating protein that conveys what the researchers describe as "superpowers" onto prostate cancer cells, causing them to aggressively spread.
MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.
A scalable "lab-on-a-chip" technology based on inkjet printing methods detected breast cancer in plasma samples from patients with more than 90% accuracy, according to a new study.
Our ability to predict who will get cancer, how a patient will respond to treatment, or if a patient will relapse is still quite limited. Despite advances in the detection of genetic mutations and the establishment of risk factors, such as age and genetic variants, it remains a great scientific and medical challenge.
Scientists have pioneered the use of whole living cells (that is, human lung adenocarcinoma) in dynamic combinatorial chemistry systems.
Cancer can sometimes remain dormant, but it usually metastasizes and spreads to new sites in the body.
How do cells move? Why do they move? Why do some cancer cells move slowly while others move quickly, causing cancerous tumors to become more difficult to treat?
Tumors are not a consistent cluster of cells. In fact, colon cancers carry differentiated-like cells, just like the functional cells of the intestinal wall and pluripotent cells—the supposed tumor stem cells.