Monoclonal Antibody News and Research

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Monoclonal antibodies (MAbs) are produced from a single B cell clone and can bind to a single type of antigen binding site. MAbs are homogenous antibodies that cannot form lattices with monomeric proteins as they can bind to only a single epitope on the antigen. Developed in the 1970s, MAbs can be produced against any given substance. Thus they can be used to detect and purify any substance of interest. This has made MAbs a powerful tool of molecular biology, biochemistry, and medicine.
Newly designed higher affinity monoclonal antibody for cancer treatment

Newly designed higher affinity monoclonal antibody for cancer treatment

Key discovery could prevent treatment failure in people with severe hemophilia A

Key discovery could prevent treatment failure in people with severe hemophilia A

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

COVID-19 virus triggers antibody response from prior coronavirus infections

COVID-19 virus triggers antibody response from prior coronavirus infections

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

New analysis technique could pave way for major breakthroughs in immunotherapy

New analysis technique could pave way for major breakthroughs in immunotherapy

Novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on HC-FIA

Novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on HC-FIA

Study reveals new target to make breast cancer more sensitive to immunotherapy

Study reveals new target to make breast cancer more sensitive to immunotherapy

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

Mutations in SARS-CoV-2 spike protein may improve monoclonal antibody resistance

Mutations in SARS-CoV-2 spike protein may improve monoclonal antibody resistance

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

Researchers identify an effective treatment for severe cases of COVID-19 infection

Researchers identify an effective treatment for severe cases of COVID-19 infection

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A simple screening process may improve mAb-based drug development

A simple screening process may improve mAb-based drug development

Rapid drug development yields potential treatment for yellow fever

Rapid drug development yields potential treatment for yellow fever

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19