Mutation News and Research

RSS

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

The CRISPR-Chip technology was first introduced in 2019 by Dr. Kiana Aran, an Assistant Professor at Keck Graduate Institute (KGI).

6 Apr 2021

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

Discovering a new genetic mutation in Schizophrenia

A new genetic mutation has been discovered in schizophrenia, and we spoke to Dr. Todd Lencz from the Feinstein Institutes for Medical Research to find out more.

From Northwell Health 1 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

Study shows how WAVE2 protein maintains the immune system balance

Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.

26 Mar 2021

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Researchers have used an upgraded version of the gene-editing tool, CRISPR/Cas9, to knock out up to 12 genes in plants in just one go.

23 Mar 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Rare genetic variants contribute to increased risk for lung cancer

In the United States, lung cancer is the main cause of cancer death in both male and female populations.

19 Mar 2021

Genetic flaw shows promise for treating eye disease

A genetic flaw may hold the key to delay or prevent the onset of a serious eye disorder that can result in blindness and vision loss.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 17 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

Three new COVID-19 variants can evade antibodies that act against original virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Researchers develop genetic patch to eliminate problems in hearing cells

They can hear well up to about forty years old, but then suddenly deafness strikes people with DFNA9. The cells of the inner ear can no longer reverse the damage caused by a genetic defect in their DNA.

3 Mar 2021

Detective work inside plant cells finds a key piece of the C4 photosynthesis puzzle

An impressive body of evidence published this week reveals the answer to a mystery that has puzzled plant scientists for more than 30 years.

3 Mar 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

New function of regulatory gene may lead to more productive plant varieties

A team of researchers has confirmed that the SUPERMAN gene also establishes the number of flowers in leguminous plants.

1 Mar 2021

Mutation News and Research

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

High expression of cell death genes linked to increased risk of dying early from lung cancer

Discovering a new genetic mutation in Schizophrenia

New AI-based method can lead to faster, low-cost development of protein-based drugs

Study shows how WAVE2 protein maintains the immune system balance

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Low representation of minority groups in genomic databases may impact therapy selection

Rare genetic variants contribute to increased risk for lung cancer

Genetic flaw shows promise for treating eye disease

Study shows how human viruses are better adapted to infect certain tissues

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

Three new COVID-19 variants can evade antibodies that act against original virus

Researchers develop genetic patch to eliminate problems in hearing cells

Detective work inside plant cells finds a key piece of the C4 photosynthesis puzzle

New technique reveals the tricks that cancer cells use to avoid immunotherapies

New function of regulatory gene may lead to more productive plant varieties

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics