Mutation News and Research

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The Association Between Type 2 Diabetes Treatment Response and Genetic Variants

People who are at a high risk of developing type 2 diabetes can be prescribed a variety of medications to decrease blood sugar levels, but it is not always apparent which people would benefit from which treatments the most.

6 Jun 2023

How Do Protons Move in Hachimoji DNA?

According to quantum biologists at the University of Surrey, revealing the potential of lab-crafted DNA, called synthetic DNA, holds the key to innovative breakthroughs across multiple domains.

6 Jun 2023

Online Prediction Modeling Tool to Help Advance Scientific Discoveries

By anticipating the location of proteins within a cell, researchers might have access to a trove of biological knowledge. Future scientific discoveries related to drug development and the treatment of diseases like epilepsy will depend on this information.

6 Jun 2023

Virally Mediated Gene Therapy Rescues Hearing in Aging Mice

By 2050, one in 10 individuals are expected to live with some form of hearing loss. Of the hundreds of millions of cases of hearing loss affecting individuals worldwide, genetic hearing loss is often the most difficult to treat.

29 May 2023

Fission Yeast Analysis Reveals Two Key Genes Involved in Gross Chromosomal Rearrangement

When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body's genetic code, DNA, which is stored in structures known as chromosomes, can bring about mutations in the body.

26 May 2023

Role of SWI/SNF Chromatin Remodeling Complex in Cell Division

A previously unknown function for the SWI/SNF chromatin remodeling complex has been revealed by researchers at St. Jude Children’s Research Hospital.

25 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Key Event that Controls the Timing of the Biological Clock Identified

Molecular clocks in our cells synchronize our bodies with the cycle of night and day, cue us for sleep and waking, and drive daily cycles in virtually every aspect of our physiology. Scientists studying the molecular mechanisms of our biological clocks have now identified a key event that controls the timing of the clock.

23 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow.

18 May 2023

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Researchers have developed a chicken egg that may be safe for people with egg white allergies. Chicken egg allergies are one of the most common allergies in children.

18 May 2023

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

16 May 2023

Discovery of Shanghai APP Mutation Offers New Avenues for Treatment of Alzheimer's Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting tens of millions of people worldwide, and it is the most common cause of dementia.

15 May 2023

Seasonal Behavior of SARS-CoV-2 is Genetically Encoded, Study Suggests

As the northern hemisphere heads into summer, we may be in for a COVID-19 reprieve. Not because the pandemic is over; the Omicron subvariant 'Arcturus' is still creeping upward and causing new symptoms.

15 May 2023

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.

12 May 2023

Mutation News and Research

The Association Between Type 2 Diabetes Treatment Response and Genetic Variants

How Do Protons Move in Hachimoji DNA?

Online Prediction Modeling Tool to Help Advance Scientific Discoveries

Virally Mediated Gene Therapy Rescues Hearing in Aging Mice

Fission Yeast Analysis Reveals Two Key Genes Involved in Gross Chromosomal Rearrangement

Role of SWI/SNF Chromatin Remodeling Complex in Cell Division

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Key Event that Controls the Timing of the Biological Clock Identified

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Discovery of Shanghai APP Mutation Offers New Avenues for Treatment of Alzheimer's Disease

Seasonal Behavior of SARS-CoV-2 is Genetically Encoded, Study Suggests

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Scarring on the Extracellular Matrix Causes Muscles to Stop Working in Duchenne Muscular Dystrophy

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

How the Natural Process of DNA Repair Fails to Cause Disease

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

CITES: Regulating the International Wildlife Trade to Preserve the Viability of Species

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

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