Mutation News and Research

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Novel means to prevent and treat gonorrhea

According to scientists from the Georgia State University’s Institute for Biomedical Sciences, producing a mutation that impedes the way the bacterial pathogen Neisseria gonorrhoeae transmits gonorrhea might provide a novel means to prevent and treat the disease.

26 Sep 2022

Novel molecular mechanism of focal adhesion kinase inhibition in HD

Principal researchers at the Brain Science Institute (BSI) of the Korea Institute of Science and Technology were said to have discovered substantially decreased activity of focal adhesion kinase (FAK) proteins that play a significant role in neurite motility and proper synapse formation in HD patients’ brain tissues.

19 Sep 2022

Encouraging breakthroughs in eliminating therapy-resistant cancer cells

The human immune system is notably adept at evading tumor cells, which construct physical barriers, adopt masks, and restrain the immune system with molecular ploys.

14 Sep 2022

Spaceflight increases the risk of developing cancer and heart disease

A groundbreaking study from the Icahn School of Medicine at Mount Sinai found that astronauts are more likely to experience mutations that could be connected to spaceflight and increase their lifetime risk of acquiring cancer and heart disease.

2 Sep 2022

Scientists demonstrate a potential new route for the generation of genetic diversity in corals

In a discovery that challenges over a century of evolutionary conventional wisdom, corals have been shown to pass somatic mutations – changes to the DNA sequence that occur in non-reproductive cells – to their offspring.

1 Sep 2022

Understanding protein structures can be more complicated than thought

When you think of proteins – the enzymes, signaling molecules, and structural components in every living thing – you might think of single strands of amino acids, organized like beads on a string.

29 Aug 2022

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022

Scientists uncover the robust mechanism used by insects

Researchers at IRB Barcelona, under the direction of Dr Marco Milan, have identified a very robust system that insects use for wing formation and regeneration.

25 Aug 2022

Novel method maps all gene expression patterns to a single reference embryo

Years of work by Trinity College Dublin developmental biologists in collaboration with colleagues at the University of Edinburgh’s MRC Human Genetics Unit has resulted in an unparalleled resource that will help researchers assess how key genes control the differentiation of tissues and organs in developing embryos.

23 Aug 2022

Circadian clock impacts cell growth, metabolism, and tumor development

Scientists from the University of California, Irvine, have defined how the circadian clock impacts cell growth, metabolism, and tumor progression in a new study.

12 Aug 2022

Fabimycin likely to be an effective treatment for drug-resistant bacteria

Bacteria that cause urinary tract infections are getting more and more resistant to many medications, and they are becoming more and more difficult to cure.

12 Aug 2022

Researchers discover antibiotic resistance genes in M. tuberculosis

More than 10,000 different Mycobacterium tuberculosis bacteria isolated from 23 different countries were subjected to a thorough investigation, which uncovered new genes linked to resistance to 13 first- and second-line novel and repurposed medicines.

11 Aug 2022

Banp indispensable for cell-cycle progression and cell survival

Zebrafish mutants were found by a team of researchers about 15 years ago. These zebrafish’s eyes did not mature properly, which explains why they are much smaller than the eyes of zebrafish found in the wild.

11 Aug 2022

Researchers make significant improvements to PubCaseFinder, the clinical decision support system

Even medical professionals with years of experience can spend hours researching potential illnesses in reliable medical sources (such as databases, books, and literature) to identify which diseases have phenotypic traits overlapping with the phenotypes of undiagnosed patients.

8 Aug 2022

Novel model system to identify new treatments for CF patients who continue to struggle without therapies

A mutation in the CFTR gene results in cystic fibrosis (CF). Despite the fact that there are many hundreds of identified mutations, not all of them can now be treated, leaving a sizable portion of CF patients without access to targeted medicines.

3 Aug 2022

Scientists develop microscopy technology that observes how new neurons struggle to reach their developmental destination

With organoids to model early growth, scientists employed a developing microscopy technology to observe that new neurons find it hard to reach their developmental goal.

1 Aug 2022

Genomics plays a major role in psychedelic drugs behavior

It can be crippling for those who suffer from conditions like depression, anxiety, and cluster headaches. In clinical research, psychedelic substances have demonstrated benefits as therapies for several ailments, but not in all cases.

1 Aug 2022

Scientists determine the contribution of DNA recombinations to genomic diversity in health and disease

Researchers from Japan’s RIKEN Center for Integrative Medical Sciences, working with colleagues from all over the world, found that recombinations of particular genomic sequences, which are reproduced millions of times in the genome of each human cell, are common in both normal and disease states.

28 Jul 2022

Researchers discover potential ways to comprehend DNA replication

Non-coding DNA, also known as “junk DNA,” has been discovered to be anything but harmless and inactive and may even play a role in the onset of cancer.

22 Jul 2022

New research shows protein movements play an important role in their ability to function

Researchers at Johns Hopkins Medicine have reported that they have interrogated the atomic structure of proteins, adding to proof that the wobbles, shakes, and quivers of proteins play an important role in their ability to operate.

18 Jul 2022