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Combining AI with Robotics and Synthetic Biology to Improve Industrial Enzymes

By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois Urbana-Champaign have dramatically improved performance of two important industrial enzymes - and created a user-friendly, fast process to improve many more.

2 Jul 2025

New Clues Reveal How Multicellularity Evolved in Early Animals

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells.

2 Jul 2025

Study Finds Protein Cleavage Essential for Healthy Cilia and Cell Signaling

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, Joubert syndrome and other ciliopathies is cut in half to perform two separate functions, both of which are fundamental to the healthy development of children.

30 Jun 2025

RNases Play Pivotal Role in Shaping the Molecular Foundation of Mendelian Disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Gene Editing Halts Symptoms of Rare Smooth Muscle Disease in Preclinical Study

Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed.

25 Jun 2025

Genetic Tool Successfully Repairs Mitochondrial Mutations in Human Cells

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor.

25 Jun 2025

UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025

Llama Antibodies Provide Broad Protection Against Multiple Coronaviruses

Researchers identify small llama-derived antibodies that neutralize multiple coronaviruses, targeting a stable region of the spike protein for broad protection.

16 Jun 2025

Flipped DNA Segments Help Fish Rapidly Evolve into New Species

Researchers have found that chunks of 'flipped' DNA can help fish quickly adapt to new habitats and evolve into new species, acting as evolutionary 'superchargers'.

13 Jun 2025

The Role of Metabolism in Bacterial Survival and Resistance

Ciprofloxacin induces bioenergetic stress in E. coli, boosting survival rates and resistance development. Metabolic shifts challenge antibiotic effectiveness.

10 Jun 2025

Cryo-EM Structures Reveal How IVD Mutations Cause Isovaleric Acidemia

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

10 Jun 2025

Unraveling the Genetic Roots of Anemia in Inflammatory Bowel Disease

One of the most frequent side effects of inflammatory bowel disease, or IBD, is iron deficiency and anemia, which can be made worse by a genetic mutation linked to Crohn’s disease, according to a study conducted by biomedical scientists at the University of California, Riverside School of Medicine.

9 Jun 2025