Neck News and Research

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Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

A novel therapeutic approach inhibits the growth of metastatic tumors in mice by coercing cancer cells into a dormant state—where they cannot proliferate.

25 Nov 2021

Researchers discover molecular mechanism that explains why moles become melanomas

Moles and melanomas are both skin tumors that come from the same cell called melanocytes. The difference is that moles are usually harmless, while melanomas are cancerous and often deadly without treatment.

24 Nov 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Brown fat protects against secondary obesity-related diseases, says study

Research demonstrated that obese individuals with active brown fat possess a healthier metabolism and utilize more energy than obese people without.

8 Nov 2021

Research uncovers key component of cellular malfunction that contributes to tumor growth

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

3 Nov 2021

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

1 Nov 2021

Researchers identify the mechanism leading to deafness in Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

6 Oct 2021

Ketone supplement may be a new therapeutic strategy for enhancing brain health in adults with obesity

New research published in The Journal of Physiology has shown that ketone supplements may be a novel therapeutic strategy for protecting and improving brain health in people with obesity.

5 Oct 2021

Researchers uncover previously unknown interactions between proteins that drive cancers

In three studies from the Cancer Cell Map Initiative, researchers uncovered previously unknown interactions between proteins that drive cancer and combined this new data to generate a map of protein pathways informing cancer outcomes.

1 Oct 2021

Gene expression changes help understand the mechanism behind noise-induced hearing loss

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

30 Sep 2021

New approach to identify molecular targets for improved prostate cancer therapy

In a new study, researchers have introduced DSER, a technique for identifying molecular targets for enhanced therapy in prostate cancer.

14 Sep 2021

Researchers generate first "atlas" of human melanocytes in the body

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) have generated the first "atlas" of human melanocytes located throughout the body.

From The University of Utah 3 Sep 2021

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

From The University of Utah 20 Aug 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

New insights on how synovial sarcoma develops and spreads

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

7 Jun 2021

Newly identified protein helps tumors evade the immune system

Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

3 Jun 2021

Scientists identify mechanism by which head and neck cancer cells subvert adjacent normal tissue

Up to half of patients with head and neck squamous cell carcinoma will experience tumor recurrence or new tumors--tumors that often spread and are difficult to treat.

28 May 2021

Lack of functional GAS2 gene causes severe hearing impairment in mice

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

10 May 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021