Neurodegenerative Diseases News and Research

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How upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020

Human stem cell models reveal neurodegeneration in glaucoma

Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.

12 Jun 2020

A protein that helps to fight viruses can also inhibit lung tissue repair

Researchers at the Francis Crick Institute have found that a protein which is initially helpful in the body’s immune response to a virus, can later interfere with the repair of lung tissue.

12 Jun 2020

Researchers identify how certain gene mutations cause ALS

Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

11 Jun 2020

Research team discovers proteins that regulate interorganelle communication

Korea Brain Research Institute (KBRI headed by Suh Pann-ghill) announced on the 2nd that the joint research team of KBRI (team led by Dr. Mun Ji-young), Seoul National University, and Pohang University of Science and Technology discovered the proteins that engage in the formation of MAM, which is the cellular signaling hub.

4 Jun 2020

Stem cell model sheds new light on neurodegeneration process

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

2 Jun 2020

Innovative two-photon microscopy enables in vivo subcellular imaging of the retina

Retina is the only part of the central nervous system that can be visualized noninvasively with optical imaging approaches.

21 May 2020

Protein modification may cause long-term consequences

Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.

20 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Study shows how organisms adapt to global warming

Environmental conditions are subject to enormous variations. For example, temperatures in Germany can vary from a hot 40 °C in the summer to a freezing −20 °C in the winter.

12 May 2020

New sampling method can more accurately detect genetic alterations in tumors

A wholistic tumor sampling method that more accurately detects genetic alterations in tumors, which are critical in allowing treatment to be personalized to each and every patient, has been developed by researchers from the Crick, Roche and The Royal Marsden NHS Foundation Trust and published in Cell Reports.

12 May 2020

Project Expands Use Of Metal Catalysts For Drug Discovery

The use of metals in drug delivery could offer major benefits, including allowing for lower dosages of a medication to achieve therapeutic effects.

7 May 2020

New tool may shed more light on neurodegenerative diseases

About 350 years ago, Robert Hooke provided an initial description of a cell in Micrographia, and since then, microscopy has played a major role in figuring out life’s rules.

6 May 2020

Boosting Levels Of Good Fats

Scientists identified two genes that can regulate levels of healthy fats, called FAHFAs, in mice.

4 May 2020

Study identifies causative factors for neurodegenerative diseases

Researchers from the HudsonAlpha Institute for Biotechnology, UCSF, and UAB have discovered a new risk factor for various neurodegenerative diseases.

29 Apr 2020

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

If an actor is not in a position to perform in the theatre, an understudy—preferably one with some practice in the role—can take that role on stage.

27 Apr 2020

How do cells react to stressful conditions?

Most often, cells are subjected to stressful conditions that can pose a serious threat to life, for example, toxins or high temperatures.

23 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

Discovery marks a critical step toward developing new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

21 Apr 2020