Pharmaceuticals News and Research

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Research substantiates nanoparticles as promising platforms for cell nano-sensors

Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.

21 Jul 2021

Study shows how to unlock CRISPR’s potential to regulate many genes simultaneously

A new technique to regulate several genes in engineered yeast cells could pave the way for the highly efficient, sustainable production of bio-based products.

19 Jul 2021

$Microcrystal electron diffraction could help obtain potential pharmaceutical structures$

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

In the process of drug development, solving structures of potential therapeutics with X-ray diffraction (XRD) has been a presumed, critical step so far.

16 Jul 2021

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.

9 Jul 2021

Nikalyte Announces New Partnership with Life Science Group Calibre Scientific

Nanoparticle deposition specialists, Nikalyte Ltd announced that the company has signed a partnership agreement with global life sciences group Calibre Scientific.

8 Jul 2021

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer. The treatment alters the function of the body's phagocytes and facilitates extensive activation of the immune system.

4 Jun 2021

Novel peptide could allow cannabis to relieve pain while avoiding side effects

Many people live with chronic pain, and in some cases, cannabis can provide relief. But the drug also can significantly impact memory and other cognitive functions.

13 May 2021

Scientists discover genes responsible for smoking-related decline in lung function

(Boston)--Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by cigarette smoking that reduces lung function and causes difficulty breathing.

12 May 2021

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

5 May 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Gene-based blood test may predict treatment success in people with metastatic melanoma

A test that monitors blood levels of DNA fragments released by dying tumor cells may serve as an accurate early indicator of treatment success in people in late stages of one of the most aggressive forms of skin cancer, a new study finds.

From New York University (NYU) 15 Feb 2021

Cell cycle of cancer cells can be disrupted using two commercially available inhibitors

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.

12 Feb 2021

Rapid Assessment of the Stability of Colloids & Dispersions

The Stabino® II from Analytik is a fast and easy-to-operate zeta potential instrument for analysing and optimising the stability of colloids and dispersions, based on measurement of streaming potential.

From Analytik Ltd 27 Jan 2021

Synthetic cannabidiol can kill bacteria that causes gonorrhoea

Synthetic cannabidiol, commonly called CBD, has been demonstrated to destroy the bacteria that cause meningitis, gonorrhea, and Legionnaires’ disease.

21 Jan 2021

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

From UC San Diego 21 Jan 2021

New method shows how pharmaceuticals induce cancer cell death

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.

20 Jan 2021

Study: Cattle feed yards emit synthetic chemical cocktails into the environment

A recent Point of Reference article, "The meat of the matter: Environmental dissemination of beef cattle agrochemicals," published in Environmental Toxicology and Chemistry, points at synthetic chemical cocktails being emitted from cattle feed yards into the environment and how they can impact our ecosystem and our health.

15 Jan 2021