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PET reveals the existence of inter-organ communication between the heart and kidneys after heart attack

Whole body positron emission tomography (PET) has, for the first time, illustrated the existence of inter-organ communication between the heart and kidneys via the immune system following acute myocardial infarction, or heart attack.

14 Jul 2020

Less addictive opioid may have the ability to slow progression of osteoarthritis

A novel preclinical study by Keck Medicine of USC researchers, published in Arthritis & Rheumatology, reveals that a potential new opioid medication may have the ability to slow the progression of osteoarthritis while being less addictive than commonly prescribed opioid drugs.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

Researchers discover promising drug candidate for treatment of brain disorders

Researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) discovered a novel chemical compound, which has the potential to became a new drug for the treatment of core symptoms of brain disorders like Down syndrome and autism.

13 Jul 2020

New start-up to exploit novel drug-transporting technology

Researchers from IRB Barcelona, the University of Barcelona (UB) and the Sant Joan de Déu Research Institute - Hospital Sant Joan de Déu (SJD) have set up Gate2Brain, a company based on a novel technology developed at IRB Barcelona to transport drugs into the brain.

10 Jul 2020

Long-term culture of human pancreatic slices as a model to study regeneration of beta cells

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.

2 Jul 2020

Research unravels molecular circuitry that controls cancer growth and spread

Research led by Queen Mary University of London has revealed novel insights into the molecular circuitry controlling cancer cell growth and spread. The findings highlight new pathways involved in these key processes of cancer progression that may represent targets for therapies.

24 Jun 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Alzheimer's: New Gene May Drive Earliest Brain Changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers.

23 Jun 2020

Cellular mechanophenotyping may help better understand tumor cells

Our ability to predict who will get cancer, how a patient will respond to treatment, or if a patient will relapse is still quite limited. Despite advances in the detection of genetic mutations and the establishment of risk factors, such as age and genetic variants, it remains a great scientific and medical challenge.

10 Jun 2020

Scientists aim to develop a gene-targeting, antiviral agent to combat COVID-19

A team of scientists from Stanford University is working with researchers at the Molecular Foundry, a nanoscience user facility located at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), to develop a gene-targeting, antiviral agent against COVID-19.

5 Jun 2020

Inhibiting host cell proteases can help prevent COVID-19 infection

How can we prevent the novel coronavirus from invading a host cell in an attempt to prevent infection?

2 Jun 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

A 'Switch' That Turns Autoimmunity Drugs Into Powerful Anti-Cancer Treatments

Scientists have discovered a way to transform antibody drugs into antibodies with powerful anti-cancer activity through a simple molecular "switch".

22 May 2020

Cell-culture based in vitro test systems for screening of antitumor drugs

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Texas A&M lab produces 3D-bioprinted bone tissues

Dr. Akhilesh K. Gaharwar, associate professor, has developed a highly printable bioink as a platform to generate anatomical-scale functional tissues. This study was recently published in the American Chemical Society's Applied Materials and Interfaces.

20 May 2020

Breaking Down the DNA Behavior of Cancer Cells

Dr. Manel Esteller speaks to AZoLifeSciences about his ground-breaking cancer research in which he uncovered the behavior of DNA in 3D models.

From University of Barcelona 13 May 2020

New DNA study can revolutionize cancer treatment

In a new study, researchers have used 3D models to disintegrate the DNA behavior of tumor cells, paving the way for innovative treatment for the disease.

11 May 2020

Novel mechanism allows the immune system to control autoimmunity, cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

7 May 2020

Anti-cancer medicine could improve current therapy for ER+ breast cancer

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive (ER+) breast cancer - the most common form of breast cancer in Australia - according to preclinical studies led by Walter and Eliza Hall Institute researchers.

7 May 2020