Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

Study identifies novel mechanism by which hair follicles lose regenerative capabilities

Hair grows from stem cells residing in hair follicles. During aging, the capability of hair follicles to grow hair is successively lost, leading to hair thinning and ultimately hair loss.

17 Mar 2021

Key protein regulates cells’ innate defense mechanisms

Scientists from the University of Illinois Chicago (UIC) have found that heparanase (HPSE) is an important regulator of innate defense mechanisms of cells.

17 Mar 2021

High-resolution map of yeast genome can shed light on development responses in higher organisms

A new study explains an effort to create the most detailed and high-resolution map of gene regulation and chromosome architecture in yeast organisms.

15 Mar 2021

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

Consumption of a diet with high fat levels increases the risk of fatty liver, obesity, cardiovascular diseases, and type 2 diabetes.

15 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Cryogenic electron microscopy helps visualize 3D structure of complex responsible for gene regulation

A research team has looked inside a human cell to visualize a multi-subunit machine that is responsible for controlling the expression of genes.

15 Mar 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Optimized nano-micelles can induce efficient genome editing in mouse brain

A research team has reported that improved nano-micelles can trigger efficient genome editing in the mouse brain.

15 Mar 2021

Scientists reveal how critical enzyme in the cell works

S-acylation is the process of chemically linking a lipid to protein via a thioester bond. It is an important process of the cell that regulates the localization and function of numerous proteins.

12 Mar 2021

Researchers generate thyroid mini-organs in the lab

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or thyroidectomy leads to symptoms like fatigue, feeling cold, constipation, and weight gain.

12 Mar 2021