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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers explore how tRNAs evolve in protein synthesis

In the process of protein synthesis, a peptide bond is formed between two amino acids that are bound to two different transfer RNAs (tRNAs). Researchers have long been perplexed as to how these tRNAs evolved to be so near to one another on the ribosome.

From Tokyo University of Science 22 Apr 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

A research team led by scientists from the Hong Kong University of Science and Technology has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.

20 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

Double-stranded RNA provoke bone loss during periodontitis

Researchers from Tokyo University of Agriculture and Technology have made a novel revelation about the processes of bone loss in gum disease (periodontitis).

19 Apr 2022

16 distinct cell populations identified in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

From Test Tube to Cell; Creating Biological Computers from RNA

In this interview, we speak to Dr. Sam Schaffter about his latest research that looked at creating biological computers using RNA and their role within research.

From National Institute of Standards and Technology (NIST) 18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

A single mutation can enhance the virulence of Zika virus

Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective-;and potentially break through pre-existing immunity.

13 Apr 2022

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

A single cell’s genome or transcriptome can reveal considerably more data about its place in biological systems than sequencing a full batch of cells, just as interviewing a single person about their health will provide specialized, personalized information hard to obtain from a big poll.

11 Apr 2022

Researchers create RNA molecules to address human pancreatic beta cells

Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.

11 Apr 2022

Researchers uncover a treasure trove of new data about RNA viruses

Ocean water samples collected around the world have yielded a treasure trove of new data about RNA viruses, expanding ecological research possibilities and reshaping our understanding of how these small but significant submicroscopic particles evolved.

8 Apr 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

Study reveals how plants activate their immune system to prevent infections caused by rain

While rain is essential for the survival of plants, it also contains bacteria and other pathogens which can cause them harm. So how do plants protect themselves from this threat?

7 Apr 2022

Certain RNA molecules may serve as markers of cellular stress in different diseases

The body's ability to respond to various types of stress is essential for maintaining health, and failure of such adaptive stress responses can trigger or worsen numerous diseases.

6 Apr 2022

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern.

6 Apr 2022

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.

6 Apr 2022

A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Researchers explore a new procedure to disrupt gene regulation

What role does DNA packing play in regulating gene activity? Fanka Rang and Kim de Luca, researchers from Jop Kind’s (group leader at the Hubrecht Institute and Oncode Investigator) group, created a way to monitor both gene activity and DNA packaging at the same time to address this topic.

5 Apr 2022

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

4 Apr 2022

RNA News and Research

Researchers explore how tRNAs evolve in protein synthesis

Little-known protein may play a role in frontotemporal lobar degeneration

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

New research shows significant variations in B-cells in women with PPD

Double-stranded RNA provoke bone loss during periodontitis

16 distinct cell populations identified in a key brain region for substance use disorders

From Test Tube to Cell; Creating Biological Computers from RNA

Spatial maps offer insights into the battle between melanoma cells and immune cells

A single mutation can enhance the virulence of Zika virus

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

Researchers create RNA molecules to address human pancreatic beta cells

Researchers uncover a treasure trove of new data about RNA viruses

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Study reveals how plants activate their immune system to prevent infections caused by rain

Certain RNA molecules may serve as markers of cellular stress in different diseases

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

A critical subset of supporting cells may lie at the origins of scleroderma

Researchers explore a new procedure to disrupt gene regulation

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

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