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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Genetic editing tools stop the spread of Culex mosquitoes

Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases.

From UC San Diego 31 May 2021

Researchers discover new genes and functionalities in bovine genome

Modern genetic research often works with what are known as reference genomes. Such a genome comprises data from DNA sequences that scientists have assembled as a representative example of the genetic makeup of a species.

27 May 2021

New plasmofluidic chip could accelerate diagnosis during current and future pandemics

Reverse transcription-polymerase chain reaction (RT-PCR) has been the gold standard for diagnosis during the COVID-19 pandemic.

27 May 2021

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Rapid Removal of gDNA from RNA Samples

Porvair Sciences has launched Chromatrap® gDNA Removal Columns that quickly remove unwanted genomic DNA (gDNA) from RNA samples.

From Chromatrap® - Porvair Sciences Ltd 26 May 2021

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

The chemotherapy drug decitabine is commonly used to treat patients with blood cancers, but its response rate is somewhat low. Researchers have now identified why this is the case, opening the door to more personalized cancer therapies for those with these types of cancers, and perhaps further afield.

25 May 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

New method helps tests large groups for SARS-CoV-2 infection

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

Researchers study the origins of life using modern ecological biosignature

While searching for signs of life, scientists often look for chemicals, biosignatures, or phenomena that suggest the presence of current or past life. However, it is not always the case that signs of life on Earth are also signs of life in other planetary ecosystems.

21 May 2021

Successful class of therapeutics attack and shut down unique and harmful genes

A potential class of therapeutics that uses synthetic nucleic acids to attack and shut down harmful genes while preventing viral spread is gathering momentum.

18 May 2021

New kind of biomolecule could play a vital role in the biology of all living things

Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.

18 May 2021

Study shows that inactivation of BRG1 leads to high genetic instability

Following the p53 tumor suppressor gene, the genes encoding two proteins of the SWI/SNF chromatin remodeling complex are the most often identified mutated.

17 May 2021

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Researchers have discovered a genetic cause of an unusual neurological disorder characterized by developmental delay, known as ataxia.

From University of Pittsburgh 10 May 2021

Supercoiling characteristic of DNA's structure controls gene expression, research shows

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling that needs to be resolved later.

10 May 2021

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

The emergence and spread of new forms of resistance remains a concern that urgently demand new antibiotics. Transcription is a vital process in bacterial cell, where genetic information in DNA is transcribed to RNA for the translation of proteins that perform cellular function.

6 May 2021

RNA News and Research

Genetic editing tools stop the spread of Culex mosquitoes

Researchers discover new genes and functionalities in bovine genome

New plasmofluidic chip could accelerate diagnosis during current and future pandemics

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Rapid Removal of gDNA from RNA Samples

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

Study could help develop peptide siRNA carrier for human oral cancer

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

New method helps tests large groups for SARS-CoV-2 infection

Researchers study the origins of life using modern ecological biosignature

Successful class of therapeutics attack and shut down unique and harmful genes

New kind of biomolecule could play a vital role in the biology of all living things

Study shows that inactivation of BRG1 leads to high genetic instability

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Supercoiling characteristic of DNA's structure controls gene expression, research shows

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

“Chemical nose” smells vital variations in unusual folding of DNA structures

Changes in protein provide a better understanding of age-related changes in the kidney

New atlas may support present and future conservation efforts to protect coral reefs

Study reveals relationship between form and function in the genetic material of dinoflagellates

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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