Rapamycin is a drug used to prevent the rejection of organ and bone marrow transplants by the body. Rapamycin is an antibiotic that blocks a protein involved in cell division and inhibits the growth and function of certain T cells of the immune system involved in the body's rejection of foreign tissues and organs. It is a type of immunosuppressant and a type of serine/threonine kinase inhibitor. Rapamycin is now called sirolimus.
University of Cologne researchers have uncovered the mechanism by which cells can get rid of mutated mitochondrial DNA (mtDNA)—the heart of each of our cells, the mitochondria.
The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.
The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.
New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.
Scientists for the first time developed a nano computing agent that regulates the function of a specific protein involved in cell movement and cancer metastasis.
A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.
Aging-US published "Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition" which reported that green tea catechins are associated with a delay in aging.
MIT biologists have answered an important biological question: Why do cells control their size? Cells of the same type are strikingly uniform in size, while cell size differs between different cell types. This raises the question of whether cell size is important for cellular physiology.
According to a recent study, targeted mutations to the genome can be instituted by splitting specific mutator enzymes and later inducing them to reconstitute.
Recent research by scientists from the University of Illinois demonstrates a process that halts the herpes simplex virus 1 from inducing severe brain damage and death.
Researchers have developed a new method that offers novel insights into cancer biology by enabling them to unravel how single cells absorb fatty acids.
Alzheimer’s disease is the most prevalent form of dementia distinguished by the accumulation of amyloid plaques in the brain.
Autophagy is essential in messenger RNA (mRNA) degradation, according to researchers from the Tokyo Institute of Technology (Tokyo Tech).
A fine balance between the production and degradation of biomolecules is required for optimal cell function. Autophagy is a mechanism through which cells break down and recycle their own components.
Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders.
Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.
A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.
For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer. University of Michigan scientists are actively researching the biological underpinnings of aging with the aim of developing interventions that could potentially help people live longer, healthier lives.
Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.
Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.