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Novel metabolic pathway that makes immunology more efficient revealed

The metabolic pathways that produce a specific type of T cell are distinct from previously assumed, according to findings from the University of Michigan Rogel Cancer Center.

21 Feb 2023

Pets help improve the mental health and wellbeing of older people

Furry, finned, or feathered, our family pets come in all shapes and sizes. But while these friendly faces keep us company at home, it's a very different story for people in aged care – many of whom must relinquish their beloved pet as a condition of entry.

21 Feb 2023

Accelerating the structure-guided discovery of chemogenetic tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells. One way is by using a tool called DREADDs, which stands for Designer Receptors Activated by Designer Drugs.

21 Feb 2023

Decline in social connections and cohesion occurs with aging

Social cohesion and connection decline in an aging population, according to a new study of one of humanity's closest relatives.

21 Feb 2023

Human sleep architecture varies substantially across seasons, study shows

Whether we're night owls or morning larks, our body clocks are set by the sun. Theoretically, changing day length and light exposure over the course of the year could affect the duration and quality of our sleep.

20 Feb 2023

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Role of probiotics and functional materials in the treatment of intestinal inflammation

Maintenance of sulfomucin is a key end point in the treatment of diarrhea and inflammatory bowel disease (IBD). However, the mechanism underlying the microbial sense to sulfomucin are poorly understood, and to date, there are no therapies targeting the secretion and maturation of sulfomucin in IBD. Considering the important role of gut microbiota in host immune regulation, maintain sulfomucin by modulating the gut microbiota is inspired.

20 Feb 2023

Unique approach harnesses plant molecules like chlorophyll to harvest solar energy

Our current solar panels aren't very efficient; they are only able to convert up to about 20 percent of the sun's energy into electricity. As a result, to generate a lot of electricity, the panels require a lot of space-;sometimes leading forests to be cut down or farms to be replaced by solar. If solar panels were more efficient, much smaller panels could make the same amount of electricity, and wouldn't claim as much land.

20 Feb 2023

Novel molecule prevents cells from infection with SARS-COV-2

The virus that causes COVID-19, called SARS-CoV-2, uses its spike protein in order to stick to and infect our cells. The final step for the virus to enter our cells is for part of its spike protein to act like a twist tie, forcing the host cell's outer membrane to fuse with the virus.

20 Feb 2023

Scientists accelerate the development of pure genetic lines by inducing mutation

Iowa State University researchers may have solved a long-standing challenge associated with accelerated development of pure genetic lines.

20 Feb 2023

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

This study is led by Dr. Anjian Xu (Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University), Dr. Min Cong (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) and Dr. Junying Ding (Beijing Key Laboratory of Basic Research with Traditional Chinese Medicine on Infectious Diseases, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University).

20 Feb 2023

Identifying antimicrobials that effectively treat AMR infections

In a potential game changer for the treatment of superbugs, a new class of antibiotics was developed that cured mice infected with bacteria deemed nearly "untreatable" in humans -; and resistance to the drug was virtually undetectable.

19 Feb 2023

Significant discovery might halt the highly destructive wheat blast

An international research collaboration led by the John Innes Centre has used innovative genomic discovery methods to show how we might halt the emerging and highly destructive disease, wheat blast.

19 Feb 2023

LLNL set off to develop vaccines to treat rheumatoid arthritis and lupus

People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory (LLNL) licensee and its' collaborations with two major pharmaceutical companies.

19 Feb 2023

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

A biomedical researcher at the Lankenau Institute for Medical Research (LIMR), part of Main Line Health, has created a groundbreaking resource for scientists seeking to develop new and better vaccines in the fight against COVID-19.

19 Feb 2023

CD5-expressing dendritic cells help to prime T cell responses against cancer

Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011.

17 Feb 2023

Location is the key for psychedelic drugs to work

Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells.

17 Feb 2023

Betalain-tomatoes confer anti-inflammatory effects against macrophages and murine colitis

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Beef, pork, chicken, and other meats contain new antioxidants, analysis reveals

Imidazole dipeptides (IDPs), which are abundant in meat and fish, are substances produced in the bodies of various animals, including humans, and have been reported to be effective in relieving fatigue and preventing dementia.

17 Feb 2023

"Poisoned" form of a protein could set off events that encourage cancer growth

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

Research News and Research

Novel metabolic pathway that makes immunology more efficient revealed

Pets help improve the mental health and wellbeing of older people

Accelerating the structure-guided discovery of chemogenetic tools

Decline in social connections and cohesion occurs with aging

Human sleep architecture varies substantially across seasons, study shows

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Role of probiotics and functional materials in the treatment of intestinal inflammation

Unique approach harnesses plant molecules like chlorophyll to harvest solar energy

Novel molecule prevents cells from infection with SARS-COV-2

Scientists accelerate the development of pure genetic lines by inducing mutation

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

Identifying antimicrobials that effectively treat AMR infections

Significant discovery might halt the highly destructive wheat blast

LLNL set off to develop vaccines to treat rheumatoid arthritis and lupus

Expert releases open-source compilation of the SARS-CoV-2 molecular structure

CD5-expressing dendritic cells help to prime T cell responses against cancer

Location is the key for psychedelic drugs to work

Betalain-tomatoes confer anti-inflammatory effects against macrophages and murine colitis

Beef, pork, chicken, and other meats contain new antioxidants, analysis reveals

"Poisoned" form of a protein could set off events that encourage cancer growth

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