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New technology efficiently detects gene mutation in blood with low error rate

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

5 May 2021

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

5 May 2021

Study reveals genetic mutation associated with exfoliation syndrome

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

5 May 2021

Mutant corn gene found to increase the amount of sugars in the seeds and leaves

An abnormal accumulation of carbohydrates—starches and sugars—in the kernels and leaves of a mutant line of corn can be traced back to a single misregulated gene, and this finding provides insights into how the plant responds to stress.

5 May 2021

Abnormal fetal development is regulated by genetics, not the intrauterine environment

The genetics of the placenta and fetus, not the mother’s intrauterine environment, regulate developmental abnormalities, including those that contribute to pregnancy loss.

5 May 2021

Study reveals relationship between form and function in the genetic material of dinoflagellates

A new study unfolds a longstanding puzzle about the connection between the function and form in the genetic material of a complex group of algae.

5 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

New nanopore sequencing tool can identify the existence of nucleobases

Nanopore technology has the potential to enable the development of portable, low-cost, small devices capable of real-time DNA sequencing.

4 May 2021

New genetic database maps how immune disorders evolve

A first-of-its-kind genetic database for autoinflammatory and autoimmune disorders has been created by Japanese researchers.

4 May 2021

Study reveals a compound found in avocados helps in the treatment of leukemia

According to recent research at the University of Guelph, a compound found in avocados may one day lead to improved leukemia treatment.

4 May 2021

Researchers devise a small-molecule cocktail to protect stem cells from stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Plant biodiversity is sensitive to precipitation changes, shows study

Water is a scarce resource in many of the Earth's ecosystems. This scarcity is likely to increase in the course of climate change.

4 May 2021

Researchers study the unique genomic organization of coral symbionts

According to recent findings, the genome of single-celled plankton, called dinoflagellates, is arranged in an extremely unusual and strange manner. The study results set the foundations for further research into these vital aquatic species and significantly broaden the understanding of what a eukaryotic genome can look like.

3 May 2021

Holographic histopathology increases imaging speed, resolution for diagnostics

Histology involves the investigation of biological tissues at the microscopic level. Histology is also known as microscopic anatomy and is commonly used to diagnose cancer and other diseases.

3 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

Distinctive "spike" proteins of SARS-CoV-2 also play a key role in the disease

Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells.

3 May 2021

New gene editing tool helps analyze the mysterious quirk of bacteria

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations.

3 May 2021

Shortage of DNA building blocks triggers inflammation

Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell.

3 May 2021

Researchers identify specific proteins that play a key role in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease.

3 May 2021

JIC-CIMMYT collaboration aims to find solutions for the world's wheat farmers and consumers

The John Innes Centre (JIC, UK) and the International Maize and Wheat Improvement Center (CIMMYT) -- two world class wheat research institutes -- have announced a strategic collaboration for joint research, knowledge sharing, and communications to further the global effort to develop the future of wheat.

30 Apr 2021