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Study: Vaping Alters DNA in Ways Similar to Smoking

Young adults who vape show chemical changes in their DNA similar to those found in young adults who smoke -; changes known to be linked to the development of cancer -; according to a new study just published in the American Journal of Respiratory Cell and Molecular Biology.

26 Sep 2024

The Lasting Effects of COVID-19 on the Brain

In the UK’s largest study to date, novel steps have been taken to gain a better understanding of the immediate and long-term effects of COVID-19 on the brain.

25 Sep 2024

Identifying Risk Factors for CAPA in COVID-19 Patients

As society adapts to COVID-19, the study of the illness and its side effects is still crucial. To ascertain the prevalence of COVID-19-associated pulmonary aspergillosis (CAPA), a severe invasive fungal infection of the lungs, in Japan, a team from Osaka Metropolitan University has combed through data.

23 Sep 2024

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the generation of cellular energy.

20 Sep 2024

Modified Nucleotides Boost saRNA Vaccine Efficacy and Protection Against SARS-CoV-2

Modified nucleotides like m5C in saRNA enhance vaccine efficacy, stability, and reduce inflammation, offering a promising approach for SARS-CoV-2 protection.

18 Sep 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

Climate Change Exacerbates Valley Fever Threat

A fungal disease called valley fever is on the rise in the western United States. It typically manifests as flu-like symptoms, but it can potentially have fatal or extremely serious side effects.

4 Sep 2024

Pan-Pathogen Deep Sequencing: A New Strategy in Combating Nosocomial Antimicrobial Resistant Bacterial Infections

Deep sequencing of bacterial cultures reveals insights into nosocomial infections and antimicrobial resistance, enhancing pathogen surveillance in hospitals.

30 Aug 2024

CDCA7's Role in DNA Methylation Maintenance Revealed in Recent Study

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off switches to regulate gene expression and help generate diverse cell types without changing the underlying DNA sequence. It is how the body ensures that brain-related genes don't get turned on in heart cells, for example.

28 Aug 2024

Clinical Trials Supported by Genetics Show Higher Success Rates

Analyzing 28,561 discontinued trials, the study reveals safety and efficacy concerns as major discontinuation factors, with genetics playing a crucial role.

23 Aug 2024

Study Uncovers Biomarkers for Low Muscle Mass, Offering Insights for Personalized Prevention

Machine learning models to analyze computed tomography (CT) images of the chest and a proteomics approach to determine blood protein biomarkers.

15 Aug 2024

Mini-Gut Model Unlocks Secrets of COVID-19 Diarrhea

Researchers at Johns Hopkins Medicine claim to have identified multiple molecular pathways linked to diarrhea caused by COVID-19, offering possible therapeutic interventions utilizing human stem cells to create a sort of “mini intestine-in-a-dish.

7 Aug 2024

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

5 Aug 2024

Multispecies Transmission of Avian Flu Virus Includes Dairy Cattle, Cats, and Raccoons

A viral spillover of the highly pathogenic avian influenza virus belonging to the hemagglutinin 5 neuraminidase 1 (H5N1) 2.3.4.4b clade among herds of dairy cattle.

5 Aug 2024

Geographic Origin Plays Key Role in Tuberculosis Infection, Harvard Study Finds

For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a new study comparing how different strains move through mixed populations in cosmopolitan cities.

2 Aug 2024

Swabbing Technique Reveals Diversity of Immune Cells in the Upper Airway

Scientists at La Jolla Institute for Immunology (LJI) have published the first-ever, in-depth analysis of immune cell memory in the upper airways of adult volunteers. Among these immune cells, the researcher spotted "tissue resident" memory cells, which stand ready to defend the airway from SARS-CoV-2 and other respiratory diseases.

1 Aug 2024

Dairy Cattle Become Hosts for Avian Flu Transmission

A new study reveals evidence that avian influenza has spilled over from birds to dairy cattle across several U.S. states, resulting in mammal-to-mammal transmission between cows and from cows to cats and a raccoon.

25 Jul 2024

Traffic-Related Ultrafine Particles Cause Mitochondrial Dysfunction in Olfactory Mucosa

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows.

25 Jul 2024

New Assay Fast-Tracks Virucidal Testing

An innovative technique that can quickly ascertain whether a virus is contagious or not has the potential to completely transform how humans respond to pandemics in the future.

24 Jul 2024

Flu Virus Exploits Immune System Weakness to Infect Cells

The majority of influenza viruses enter animal or human cells through particular surface-based pathways. It has recently been found by researchers at the University of Zurich that some influenza viruses, both human and avian, can also enter cells through a second entry point that involves an immune system protein complex.

18 Jul 2024