Ribosome News and Research

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Study reveals specialized mechanism for translation of mitochondrial genome into proteins

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

23 Feb 2021

Scientists discover how the 3D structure of eye-lens proteins is formed

The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells.

11 Feb 2021

New protein quality control system could enhance full-length translation in bacteria

Professor Sang Woo’s research group has designed a synthetic protein quality control system to improve the full-length translation in bacteria.

9 Feb 2021

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly in human cells requires factors that have no counterparts in simpler model organisms.

23 Nov 2020

Study shows how coronavirus block cells’ ability to produce protective proteins

One of the novel coronavirus' most insidious tricks is that it can block the ability of cells to produce protective proteins without hindering its own ability to replicate.

6 Nov 2020

New approach to determine the structure of large RNA molecules

Researchers have designed a new technique to establish the structures of huge RNA molecules at high resolution.

9 Oct 2020

Study reveals new gene involved in motor neuron diseases

According to a study, failures in a quality control system that defends protein-building fidelity in cells can result in motor neuron degeneration.

18 Sep 2020

Scientists advance genetic understanding of the tree of life

The African baobab tree (Adansonia digitata) is called the tree of life. Baobab trees can live for more than a thousand years and provide food, livestock fodder, medicinal compounds, and raw materials. Baobab trees are incredibly significant. However, there are growing conservation concerns and until now, a lack of genetic information

28 Aug 2020

Study sheds light on the function of ribosome binding sites

Genome sequencing of plants, bacteria, and even human beings has turned out to be a standard process, but despite this fact, the genome continues to raise several unanswered questions.

28 Aug 2020

Study shows how the coronavirus disarms the body’s innate immune system

Scientists have established how SARS-CoV-2 suppresses the production of proteins in infected cells and how this virus effectively disarms the immune system.

20 Jul 2020

SARS-CoV-2 protein effectively shuts down host protein production, shows study

A detailed study of a SARS-Cov-2 protein, Nsp1, with a central role in weakening the host anti-viral immune response shows that it effectively shuts down production ofproteins in the host.

20 Jul 2020

Study shows how cells respond to nutrient deprivation

The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell's organelles as power plants, factories, roads, libraries, warehouses and more.

17 Jul 2020

Modified mRNAs improve efficiency of protein synthesis

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired.

17 Jul 2020

Study reveals a new method for efficient production of proteins

Researchers have studied over 30,000 variants of genetic sequences to determine which traits of mRNA can enhance translational efficiency.

1 Jun 2020

Research provides new insight into how molecular machines are built in living cells

New findings about critical cellular structures have upended common assumptions about their formation and composition and provided new insight how molecular machines are built in living cells.

8 May 2020

Faulty mRNA in gene expression may contribute to neurodegenerative disorders

Complex organisms experience growth, followed by the transcription of these genes into RNA, and subsequently the translation of that transcript into proteins.

4 May 2020

Hyperosmotic stress induces phase separation of the proteasomes

Cellular proteostasis is regulated by a crucial proteolytic machine called proteasome via selective degradation of ubiquitylated proteins.

29 Apr 2020

Def gene essential for maintaining liver homeostasis and regeneration capacity

Hepatocytes are responsible for diverse metabolic activities in a liver. Proper ribosome biogenesis is essential to sustain the function of hepatocytes.

28 Apr 2020

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

If an actor is not in a position to perform in the theatre, an understudy—preferably one with some practice in the role—can take that role on stage.

27 Apr 2020

Researchers decode the mechanism of antibiotic resistance in Staphylococcus

The Structural Biology Lab at Kazan Federal University and the Institute of Proteins at the Russian Academy of Sciences represent the Russian side for the current study.

8 Apr 2020