Skin cancer is the most common type of cancer in the U.S. It occurs in more than a million people each year, including many older people. There are three main types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma. Of the three, melanoma is the most serious. Skin cancer occurs when abnormal cells form and multiply in an uncontrolled way in the epidermis, or abnormal cells from the epidermis invade the dermis of the skin. Basal cell carcinoma, squamous cell carcinoma, and melanoma are skin cancers that are named for the epidermal cells from which they develop.
Researchers at Huntsman Cancer Institute at the University of Utah (U of U) have generated the first "atlas" of human melanocytes located throughout the body.
A recent study by the University of Oxford and co-workers identifies that the effects of an individual’s genes on their chance of getting sick declines with age.
According to recent research, the mutations giving rise to melanoma are the outcome of a chemical conversion in DNA triggered by sunlight.
Scientists from the RIKEN Center for Biosystems Dynamics Research (BDR) successfully created the first genetically engineered marsupial. The research and its findings published in the Current Biology journal help decipher the genetic background of special characteristics found only in marsupials.
By putting a piece of soft, strain-sensing sheet on the skin may be able to detect skin disorders non-invasively and in real-time very soon.
Melanoma accounts for only about 1% of skin cancers but leads to most of the skin cancer-related deaths.
Parkinson’s disease is a neurodegenerative disorder and melanoma is a type of skin cancer but on the surface, these disorders do not seem to have much in common.
A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant melanoma.
Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients' gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.
A test that monitors blood levels of DNA fragments released by dying tumor cells may serve as an accurate early indicator of treatment success in people in late stages of one of the most aggressive forms of skin cancer, a new study finds.
In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.
Researchers have quantified the diverse types of genomic DNA variations that take place in skin cells and found that mutations from UV light is common.
An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system (*1) in recognizing and repairing DNA that has been damaged by ultraviolet (UV) light.
Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.
Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.
Research led by Queen Mary University of London has revealed novel insights into the mechanisms employed by melanoma cells to form tumours at secondary sites around the body.
Gene therapy offers an excellent potential for treating specific types of genetic defects and cancer, immunological diseases, infections, and wounds.
Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UC San Francisco scientist who led a new study to detect DNA mutations in individual skin cells.
Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers of Karlsruhe Institute of Technology (KIT) have demonstrated that DNA damage may also occur far away from the point of incidence of the radiation.
Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.