Skin Cancer News and Research

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Skin cancer is the most common type of cancer in the U.S. It occurs in more than a million people each year, including many older people. There are three main types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma. Of the three, melanoma is the most serious. Skin cancer occurs when abnormal cells form and multiply in an uncontrolled way in the epidermis, or abnormal cells from the epidermis invade the dermis of the skin. Basal cell carcinoma, squamous cell carcinoma, and melanoma are skin cancers that are named for the epidermal cells from which they develop.

Genomic Deletions Drive Development of Melanoma Drug Resistance

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

15 Apr 2024

CD4+ T Cells Revealed as Powerful Cancer Killers

Researchers have unveiled groundbreaking insights into CD4+ T cells, a kind of immune cell, demonstrating the potential for immunotherapies targeting melanoma, the most fatal kind of skin cancer.

22 Jan 2024

Unveiling Epidermal Hemoglobin: A Breakthrough in Skin Research

Scientists have, for the first time, demonstrated the presence of hemoglobin—a protein primarily known for its role in binding with oxygen within red blood cells—in the epidermis, the outermost tissue layer of human skin.

20 Nov 2023

Naked Mole Rat Gene Boosts Mouse Health and Longevity

University of Rochester scientists have successfully transmitted a longevity gene from naked mole rats to mice, resulting in better health and an extension of the mouse’s lifespan.

24 Aug 2023

Photoacoustic Spectral Analysis Shows Promise for Noninvasive Diagnosis of Tumors

Tumors are not just isolated clumps of abnormal cells but are associated with more complex system known as the "tumor microenvironment" (TME).

14 Jun 2023

Gut Microbiome and Enhanced Tumor Immune Response in Pancreatic Cancer Survivors

Even as pancreatic cancer treatments advance, only around 9% of patients live beyond five years. Scientists have failed to identify genetic distinctions that explain why some patients live for a long time and others do not, so they have moved their emphasis to the gut microbiome.

5 Apr 2023

Clearance of senescent cells by boosting anti-viral immune response

Aging, or senescent cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

31 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

CD5-expressing dendritic cells help to prime T cell responses against cancer

Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011.

17 Feb 2023

Researchers use artificial human skin to block invasive tumor growth in skin cancer model

By using artificial human skin, a research group from the University of Copenhagen have managed to block invasive growth in a skin cancer model.

27 Jan 2023

New approach to clear early stage pre-cancerous tumor cells

A novel method of reprogramming the immune cells to shrink or destroy cancer cells has been demonstrated to work in melanoma, a difficult to treat and destructive skin cancer.

1 Nov 2022

Antibiotics deplete intestinal flora and weaken the immune response

According to a recent study conducted by scientists at Emory University in Atlanta, the administration of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive type of skin cancer, expedited their metastatic bone growth.

12 Sep 2022

Researchers find active protein in tumor cells might help in new cancer treatments

A discovery regarding how a particular protein is triggered in tumor cells, conducted by researchers at the University of California, Irvine, may lead to more effective therapies for some of the deadliest types of cancer.

20 Jul 2022

Researchers get a complete atlas of zebrafish genetic data for biomedical research

According to the latest research, medical and life science scientists will benefit from the most detailed atlas of zebrafish genetic data available.

5 Jul 2022

Research sheds light on mechanism for skin cell death, likely to help treat cancer

Researchers at Emory University have uncovered a mechanism for skin cell death that might lead to novel therapies for “flesh-eating” infections, alopecia, hives, and possibly even melanoma, the deadliest type of skin cancer.

18 May 2022

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is an incurable, rare cancer of skin-homing T cells that is highly disfiguring and lethal at advanced stages.

2 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

23 Feb 2022

Study shows how skin cells act as a firewall against cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body's natural defenses against the development of skin cancer.

12 Jan 2022