Streptococcus pneumoniae, or Pneumococcus, is a very common bacterial infection in both industrialized and developing countries. In particular, young children and the elderly represent high-risk populations of developing pneumococcal infections. According to the WHO, the bacterium kills up to one million children under the age of five years each year worldwide. It accounts for many Bacterial Meningitis cases in adults and it is the most common cause of Bacteraemia, Pneumonia, Meningitis and Otitis media in young children.
Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome).
New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal.
Jacqueline Kimmey speaks to AZoLifeSciences about her research into bacterial pneumonia and the genes that drive its spread from the lungs into the blood.