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Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Experts explore how DNA packaging affects gene regulation

Russian researchers have elucidated the mechanisms involved in the activation of genes in drosophila fly sex cells.

24 Feb 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Study highlights how IL-2 regulates developmental bifurcation

The immune system is a complicated network of cells and proteins that performs a straightforward function—protecting the body against infection.

15 Feb 2022

Study shows how natural products inhibit SARS-CoV-2 main protease Mpro

The fight against the COVID-19 pandemic is a worldwide scientific issue including the development of measures to combat the virus and its harmful effects.

From University of Barcelona 14 Feb 2022

Dresden researchers explain how liquid-like protein droplets read DNA regions

A single cell forms the basis of life. As an organism grows, dividing cells specialize to produce the many tissues and organs that make up the adult body.

From The Max Planck Institute 14 Feb 2022

Sewer slime can accumulate SARS-CoV-2 RNA, study reports

During the COVID-19 pandemic, monitoring the levels of SARS-CoV-2 RNA in wastewater entering treatment plants has been one way that researchers have gauged the disease's spread.

10 Feb 2022

Study shows how root symbiosis with fungi is driven by the plant’s phosphate status

Phosphorus is one of the most important nutrients for plants. Among other functions, it is needed to create substances for the plant’s immune system, for the healthy development of seeds and for root growth.

9 Feb 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Researchers make new advances in connecting the evolution of pregnancy and cancer metastasis

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

Study provides insight into replication and transcription machinery of ranaviruses

Nucleo-cytoplasmic large DNA viruses (NCLDVs) of the genus Ranavirus (family iridoviridae) have been isolated from aquatic species such as reptiles, amphibians, and bony fish. Poikilotherms are at risk from these promiscuous infections.

21 Jan 2022

Researchers develop a three-dimensional, fully dynamic kinetic model of a living minimal cell

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

21 Jan 2022

Researchers determine how key protein drives the defense system to fight viruses

Scientists have just found a solution to a major mystery that explains how human blood cells train the defense system against viruses. They hope that this discovery will one day allow them to better control the response and either boost or calm it as needed.

13 Jan 2022

Study may pave the way for designing next generation of artificial chromosomes for data storage

Previously, researchers from Tianjin University designed and created a 254 kb digital data carrying artificial chromosome in yeast.

12 Jan 2022

Research shows how bacteria silence potentially deadly genes

Humans are all made of collections of cells, where each cell contains instructions in the DNA to become another cell.

7 Jan 2022

Lack of genetic switch results in malformations during embryonic development

A group of researchers identified how a minor disturbance in the activation mechanism of this gene triggers the origin of clubfoot, a common foot malformation.

17 Dec 2021

INTEGRA offers answers to your cell culture throughput needs

With INTEGRA electronic pipettes, you can program and store pipetting protocols and mixing routines for use across various workflows.

From INTEGRA Biosciences 14 Dec 2021

Study details the design of RNA-based breathalyzer to diagnose SARS-CoV-2

In a new study in The Journal of Molecular Diagnostics, published by Elsevier, investigators report on the design and testing of a breathalyzer, known as the Bubbler, that relies on viral RNA detection to diagnose SARS-CoV-2. Its name is derived from the bubbling sound that occurs when the patient exhales into the device.

14 Dec 2021

Study reveals the biochemistry of long-term memory consolidation

Scientists from Tokyo Metropolitan University recently gained a deeper understanding of the biochemistry of long-term memory.