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Immune system–related differences in dialysis, kidney transplant patients are amplified by SARS-CoV-2

People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19.

8 Nov 2021

OHSU part of new project investigating stem cell therapy as potential glaucoma treatment

Oregon Health & Science University is part of a national research project investigating stem cell therapy as a potential treatment for glaucoma, the world's second leading cause of blindness.

1 Nov 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers identified a greatly potent monoclonal antibody that aims at the spike protein of SARS-CoV-2.

19 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Scientists show how skin T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

15 Oct 2021

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.

22 Sep 2021

Stem cell transplantation leaves no scars in the DNA of transplanted cells

Stem cell transplants do not lead to changes in the DNA of the donor cells. That's according to a new study, which provides important evidence for the safety of this procedure.

8 Sep 2021

New framework to evaluate the risks of antibiotic resistance genes

Scientists have created a useful framework to assess the risks of antibiotic resistance genes (ARGs).

8 Sep 2021

Study employs llama nanobodies to hunt human cytomegalovirus

Researchers created a “nanobody”, a small fragment of a llama antibody, that can evade human cytomegalovirus as it hides away from the immune system.

26 Jul 2021

Researchers successfully create genetically engineered marsupials via genome editing

Scientists from the RIKEN Center for Biosystems Dynamics Research (BDR) successfully created the first genetically engineered marsupial. The research and its findings published in the Current Biology journal help decipher the genetic background of special characteristics found only in marsupials.

23 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Single mutation leads to rare genetic muscle disease

The origin of rare, severe muscle disease has been uncovered by an international team of researchers headed by the University of Bonn (Germany).

16 Jun 2021

Diet plays a crucial role in liver disease outcome, mouse model shows

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD patients are at higher risk of developing Non-alcoholic steatohepatitis (NASH), which causes severe and chronic liver inflammation, fibrosis and liver damage.

2 Jun 2021

New gene editing approach bypasses disease-causing mutations

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

From Penn State University 22 Apr 2021

Transplant News and Research

Immune system–related differences in dialysis, kidney transplant patients are amplified by SARS-CoV-2

OHSU part of new project investigating stem cell therapy as potential glaucoma treatment

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Scientists show how skin T cells can damage other organs in stem cell transplant patients

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

Stem cell transplantation leaves no scars in the DNA of transplanted cells

New framework to evaluate the risks of antibiotic resistance genes

Study employs llama nanobodies to hunt human cytomegalovirus

Researchers successfully create genetically engineered marsupials via genome editing

Universal stem cells exhibit the potential for more cost-effective cell therapy

Single mutation leads to rare genetic muscle disease

Diet plays a crucial role in liver disease outcome, mouse model shows

New gene editing approach bypasses disease-causing mutations

3D biomaterial helps implanted stem cells stick around to reverse arthritis

Study shows autism spectrum disorder is related to changes in the gut microbiome

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

Non-circulating memory T cells contribute to chronic transplant rejection

Study shows beneficial effects of gene therapy can be observed even after several decades

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