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Cancer cells disarm immune cells by hijacking mitochondria, says research

Researchers utilized the power of nanotechnology to identify a novel means that cancer cells use to disarm their would-be cellular attackers.

19 Nov 2021

New group of molecules that have an antibacterial effect identified

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria.

18 Nov 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

New technique anticipated to deliver personalized immunotherapies for cancer

Recent research led to a very effective technique to create many immune cells particularly engineered to identify neoantigens.

17 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Study shows how a common gene mutation robs people of natural cancer protection

Scientists from the University of Virginia School of Medicine have identified how a common gene mutation deprives people of natural protection against cancer.

15 Nov 2021

Using a new genetic technology to decipher intratumoral heterogeneity

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

12 Nov 2021

Targeting Shp2 as a cancer therapy may worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

10 Nov 2021

Whole genome sequencing for children with cancer provides accurate diagnosis

According to a new study, revealing the entire genetic code for each child diagnosed with cancer could unravel new treatment options.

10 Nov 2021

Experts identify novel mechanisms involved in macrophage polarization

Macrophages are important cells of the immune system with numerous beneficial functions. However, macrophages also aggravate common diseases.

8 Nov 2021

Research uncovers key component of cellular malfunction that contributes to tumor growth

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

3 Nov 2021

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.

3 Nov 2021

Study reveals what causes T cells to be non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

1 Nov 2021

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

1 Nov 2021

Cancer cells change their shape and migration modes more often, says research

Recent research from the Oregon State University shows how malignant cells change their shape and migration techniques to attack various tissues.

29 Oct 2021

Study provides novel insights into how cells move through the body

Recent research published in eLife revealed that cells can control their capability to migrate throughout the body with the help of a protein named fascin.

29 Oct 2021

Intussusceptive angiogenesis contributes to growth of daughter tumors in malignant melanoma

For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of new blood vessel branches, but also an alternative process in which one blood vessel divide into two parallel vessels bylongitudinal splitting.

28 Oct 2021

Study offers novel therapeutic opportunities to prevent breast tumor recurrence

Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.

28 Oct 2021

Research reveals how cancer cells thrive by exploiting genetic and cellular processes

Writing in EMBO reports, researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe how a pair of fundamental genetic and cellular processes are exploited by cancer cells to promote tumor survival and growth.

From UC San Diego 27 Oct 2021

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Ghent University’s concentrated on a technique for the safe engineering of therapeutic cells with photothermal nanofibers for the past decade.

26 Oct 2021