Tumor News and Research

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Biologists unravel how tissue geometry influences cell migration

Cells move constantly throughout our bodies, performing myriad operations critical to tissue development, immune responses, and general wellbeing. This bustle is guided by chemical cues long studied by scientists interested in cellular migration.

23 Nov 2020

Novel DNA-based nanogel for targeted delivery of chemotherapeutics

Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells.

19 Nov 2020

New method could more sensitively detect circulating tumor cells

Breast cancer is the most frequently diagnosed cancer in women, and metastasis from the breast to other areas of the body is the leading cause of death in these patients.

19 Nov 2020

Study shows CRISPR/Cas9 system can effectively treat metastatic cancers

Researchers have shown that the advanced CRISPR/Cas9 system is extremely effective in curing metastatic cancers.

19 Nov 2020

Researchers explain how tissue tension influences the orientation of cell division

The human body experiences many cell divisions during a lifetime. Such a biological process is crucial to form and sustain organs and tissues inside the body.

18 Nov 2020

Presence of microbes in the lung can modulate lung cancer pathogenesis

Bottom Line: Enrichment of the lungs with oral commensal microbes was associated with advanced stage disease, worse prognosis, and tumor progression in patients with lung cancer.

12 Nov 2020

Genetic signature in localized prostate cancer can predict likelihood of tumor metastases

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Study shows how UCH37 enzyme regulates a cell’s waste management system

Researchers reported the discovery of a new enzyme, called UCH37, that controls the waste management system of a cell.

9 Nov 2020

White blood cells can be trained to attack tumor cells

Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

9 Nov 2020

New method to improve preclinical evaluation of CAR-T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.

9 Nov 2020

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

6 Nov 2020

Epigenetic clock predicts the future growth of cancer cells

A team of researchers from IDIBAPS-Hospital Clínic and the University of Barcelona has headed an international study to design an epigenetic clock that can track the amount of cancer cells that have multiplied previously.

5 Nov 2020

Study sheds new light on key protein implicated in tumor development

A study headed by the University of Colorado Boulder has revealed a specific protein that is crucial for regulating the growth, proliferation, and function of cells, and how these cells were long implicated in the development of tumors.

5 Nov 2020

Teratomas could provide a new glance at human development

Finding just the right model to study human development--from the early embryonic stage onward--has been a challenge for scientists over the last decade.

5 Nov 2020

Researchers identify evolutionarily conserved pathway responsible for "closing down" gene activity

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for "closing down" gene activity in the mammalian cell.

3 Nov 2020

Pancreatic cancer cells avert starvation by signaling to nerves, shows study

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online on November 2 in Cell.

3 Nov 2020

MUSC researchers demonstrate polarized Th17 cells can effectively eradicate tumors

Adoptive transfer of T-cells can extend survival and, at times, treat patients with advanced solid tumors.

2 Nov 2020

Study probes mechanism by which COVID-19 distribution in the body damages erythrocytes

Experts have investigated the mechanisms of COVID-19 inside-the-body distribution related to the damage of erythrocytes.

2 Nov 2020

Checkpoint inhibitors offer a promising solution for hard-to-treat cancers

Cancer immunotherapies, which empower patients' immune systems to eliminate tumors, are revolutionizing cancer treatment. Many patients respond well to these treatments, sometimes experiencing long-lasting remissions. But some cancers remain difficult to treat with immunotherapy, and expanding the impact of the approach is a high priority.

2 Nov 2020

New type of cancer immunotherapy trains the immune system to eliminate tumor cells

A groundbreaking new type of cancer immunotherapy developed at the Icahn School of Medicine at Mount Sinai trains the innate immune system to help it eliminate tumor cells through the use of nanobiologics, tiny materials bioengineered from natural molecules that are paired with a therapeutic component, according to a study published in Cell in October.

2 Nov 2020