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The Role of Yeast Ribosomes in Cellular Survival During Starvation

Researchers from EMBL Heidelberg and the University of Virginia School of Medicine have uncovered a fascinating mechanism by which cells respond to nutrient deprivation. This discovery holds intriguing implications for understanding cancer development.

10 Oct 2024

New Method for Identifying Kinase Inhibitors for Cancer Therapy

The most difficult subtype of breast cancer to treat is triple-negative breast cancer (TNBC). Over 20,000 cases of TNBC are reported each year in the United States alone.

10 Oct 2024

CAR-NKT Cells Show Promise in Overcoming Solid Tumor Barriers

Chimeric antigen receptor T-cell therapy (CAR-T) has shown significant promise in the treatment of blood malignancies in the fight against cancer.

8 Oct 2024

UNC Researchers Unveil CAR-NKT Therapy for Enhanced Antitumor Activity

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

8 Oct 2024

Genes2Genes Unlocks New Potential for Detecting Gene Expression Changes

Genes2Genes an accurately infer alignments in simulated and real datasets of single-cell trajectories and capture sequential mismatches and matches in individual genes.

4 Oct 2024

Study: Vaping Alters DNA in Ways Similar to Smoking

Young adults who vape show chemical changes in their DNA similar to those found in young adults who smoke -; changes known to be linked to the development of cancer -; according to a new study just published in the American Journal of Respiratory Cell and Molecular Biology.

26 Sep 2024

High-throughput screening identifies potential drugs for low-grade serous ovarian cancer

In a recent study, researchers used high-throughput drug screening to identify potential therapeutic targets and novel treatments for low-grade serous ovarian cancer (LGSOC), offering hope for more effective and personalized therapies.

26 Sep 2024

A New Understanding of the Effects of Fever on Immune Cells

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also -; in a particular subset of T cells -; cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

23 Sep 2024

Lipids Found to Play Key Role in Cancer Immune Evasion

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes.

18 Sep 2024

New Insights into How Mutant p53 Promotes Tumor Growth

Research from the Federal University of Rio de Janeiro (UFRJ) and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB) in Brazil has uncovered a critical mechanism by which mutations in the p53 protein-;a key tumor suppressor known as the "guardian of the genome"-;turn other proteins into cancer-promoting agents

17 Sep 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

CHIEF Model Transforms Cancer Evaluation with Enhanced Generalizability Across Diverse Histopathology Samples

The CHIEF model revolutionizes cancer diagnosis, leveraging histopathological imaging to predict tumor origins and survival outcomes with exceptional accuracy.

16 Sep 2024

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.

9 Sep 2024

Common Skin Fungus Identified as a Potential Factor in Tumor Growth

A common skin fungus, Malassezia globosa may invade deep tissues through the skin or by other means, then cause tumor growth, according to a new study.

6 Sep 2024

AMLo Biosciences Receives UKCA Mark for Groundbreaking Melanoma Biomarker Test

AMLo Biosciences Ltd (Newcastle upon Tyne, UK) announces the successful receipt of the UKCA mark for AMBLor. AMBLor is a groundbreaking histopathological biomarker test for the personal identification of early-stage melanomas at low risk of progression, post staging diagnosis.

6 Sep 2024

CRISPR/Cas System Revolutionizes Tumor Variant and Biomarker Detection

The CRISPR-Cas system is transforming tumor biomarker detection, enabling ultra-sensitive diagnostics and improving accuracy in cancer detection and monitoring.

4 Sep 2024

Scientists Discover How AML Cells Use P-Bodies to Sustain Growth

An international team of scientists has uncovered a mechanism by which acute myeloid leukemia (AML) cells sustain their growth.

22 Aug 2024

Exploring Retrotransposon-Derived DNA Zip Codes in Myeloma Cell Internalization

A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, "Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization."

12 Aug 2024

Lipid Nanoparticle-Encapsulated miR-193a-3p Mimic INT-1B3 Boosts Anti-Tumor Immunity

A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, "INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death."

6 Aug 2024

Revealing the Spatial Dynamics of Sebum Production

Changes in gene expression in sebaceous glands have been spatially mapped for the first time in a collaborative project between Leipzig University's Interdisciplinary Centre for Bioinformatics (IZBI) and the Faculty of Veterinary Medicine.

1 Aug 2024