Tumor News and Research

RSS

New technology efficiently detects gene mutation in blood with low error rate

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

5 May 2021

Holographic histopathology increases imaging speed, resolution for diagnostics

Histology involves the investigation of biological tissues at the microscopic level. Histology is also known as microscopic anatomy and is commonly used to diagnose cancer and other diseases.

3 May 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

New, altered form of prolactin receptor found to drive breast cancer

Prolactin is a hormone that has long been thought to play an important role in breast development and growth, as well as milk production during pregnancy.

27 Apr 2021

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

A new study has shown that it is viable to reduce tumor growth by a therapy that involves tagging cancer cells with various therapeutic molecules.

26 Apr 2021

Researchers hope to make estrogen therapy a more accessible treatment for breast cancer patients

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

Cutting-edge genomic tools used to investigate health effects of Chernobyl radiation exposure

In two landmark studies, researchers have used cutting-edge genomic tools to investigate the potential health effects of exposure to ionizing radiation, a known carcinogen, from the 1986 accident at the Chernobyl nuclear power plant in northern Ukraine.

23 Apr 2021

Small molecular changes can have dramatic impact on the CAR T cell function

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't respond, they went back to the drawing board to determine why.

23 Apr 2021

Study shows how stem cells make specific types of cells

With the help of a novel single-cell technique, researchers from the Walter and Eliza Hall Institute (WEHI) have revealed a new way to interpret the programming behind stem cells and how these cells make specific types of cells.

16 Apr 2021

DNAJC9 protein plays a key role in protecting histones in the cell nucleus

Histones play an important role in the cell nucleus by packaging DNA into chromatin.

15 Apr 2021

Cancer immunotherapy patients experience potentially life-threatening side effects

Many patients with cancer receive immune checkpoint inhibitors that strengthen their immune response against tumor cells. While the medications can be life-saving, they can also cause potentially life-threatening side effects in internal organs.

13 Apr 2021

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

Exercise training may slow tumor growth for females with breast cancer

Exercise training may slow tumor growth and improve outcomes for females with breast cancer - especially those treated with immunotherapy drugs - by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have found.

13 Apr 2021

Study compares effect of vaping and smoking on cells and DNA

Researchers have compared vape e-liquid samples and their aerosols to combustible cigarette smoke using Toxys’ ToxTracker range of in-vitro assays.

12 Apr 2021

A new way to predict positive outcomes of immunotherapy in patients with bladder cancer

Researchers have detected and validated groups of genes linked to immunotherapy resistance in patients with metastatic urothelial cancer of the bladder.

12 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

According to a study, DNA defects in the energy “factories” of a cell increase the chance of survival in patients suffering from bowel cancer.

9 Apr 2021

Researchers upend the models of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

8 Apr 2021

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Researchers have discovered how specific proteins ensure the rectification of errors introduced into the DNA when it replicates.

7 Apr 2021

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Tumor News and Research

New technology efficiently detects gene mutation in blood with low error rate

Holographic histopathology increases imaging speed, resolution for diagnostics

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

New, altered form of prolactin receptor found to drive breast cancer

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

Researchers hope to make estrogen therapy a more accessible treatment for breast cancer patients

Cutting-edge genomic tools used to investigate health effects of Chernobyl radiation exposure

Small molecular changes can have dramatic impact on the CAR T cell function

Study shows how stem cells make specific types of cells

DNAJC9 protein plays a key role in protecting histones in the cell nucleus

Cancer immunotherapy patients experience potentially life-threatening side effects

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Exercise training may slow tumor growth for females with breast cancer

Study compares effect of vaping and smoking on cells and DNA

A new way to predict positive outcomes of immunotherapy in patients with bladder cancer

New method can improve the drug testing process

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

Researchers upend the models of cancer metabolism

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

Developing a portable tool to detect street drug ‘spice’

National DNA Day: Importance of DNA in Research

National DNA Day 2021: An Interview with Professor George Church

Latest Life Science News