Tumor News and Research

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New computer model helps identify mutations that drive tumor growth

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

22 Jun 2022

Researchers understand the mystery behind DNA rings

Professor Dr Anton Henssen of Charité – Universitätsmedizin Berlin and the Helmholtz Association’s Max Delbrück Center (MDC) for Molecular Medicine, along with a group of researchers from the United States and the United Kingdom, have received a grant for a Cancer Grand Challenge.

17 Jun 2022

Novel nanoparticle therapeutic shows potential for treating human cancers

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

15 Jun 2022

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Gene expression analysis helps identify genes that cause endocrine resistance in breast cancer

The most prevalent type of cancer detected in women is breast cancer (BC). BC is the second biggest cause of death among female cancer patients globally.

9 Jun 2022

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

The formation of aqueous droplets in macromolecules by liquid-liquid phase separation (or coacervation) is a popular topic in life sciences research. DNA is particularly interesting among the numerous macromolecules that form droplets because it is predictable and programmable, both of which are desirable properties in nanotechnology.

6 Jun 2022

Researchers analyze the involvement of immune cells in lung cancer survival

Lung cancer affects approximately 48,500 persons in the United Kingdom every year. New treatments are urgently needed because only around 20% of patients live 5 years after diagnosis, and it is the leading cause of cancer death.

1 Jun 2022

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

The University of Texas MD Anderson Cancer Center scientists have created an ultrasound-guided cancer immunotherapy approach that promotes systemic antitumor immunity and increases immune checkpoint blockade therapeutic potential. Nature Nanotechnology published the results of the pioneering study.

1 Jun 2022

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

1 Jun 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

An immunological problem has been addressed by scientists at St. Jude Children’s Research Hospital. Despite being genetically identical, a CD8+ T cell can divide and produce two functionally different daughter cells.

27 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Cancer biomarkers relying on methylation could forecast tumor type

In cancer management, biomarkers are commonly used to guide treatment decisions and evaluate patient outcomes.

23 May 2022

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Many cancers include genetic “hotspots,” or sections of DNA that are subject to mutation. For example, a mutation in the TP53 gene is found in more than 50% of all cancers, generally within a narrow DNA range.

18 May 2022

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Prostate cancer that has spread to other regions of the body is commonly treated with hormone treatment, but many individuals develop resistance to it, making their disease more aggressive and potentially fatal.

12 May 2022

Study shows new potential target for CAR T cells to inhibit solid tumors

CAR T therapy, or chimeric antigen receptor T-cell therapy, has revolutionized the treatment of some blood cancers, allowing patients with relapsed or refractory disease to live longer and better lives.

10 May 2022

Gene expression signatures in lymph node cells play an active role in lymphoma development

Researchers from the University of Tsukuba identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of lymphomas.

3 May 2022

Tumor News and Research

New computer model helps identify mutations that drive tumor growth

Researchers understand the mystery behind DNA rings

Novel nanoparticle therapeutic shows potential for treating human cancers

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers discover a new interferon-gamma receptor signaling pathway

Gene expression analysis helps identify genes that cause endocrine resistance in breast cancer

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

Researchers analyze the involvement of immune cells in lung cancer survival

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers devise a new treatment approach to cure aggressive brain tumors

Cancer biomarkers relying on methylation could forecast tumor type

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Study shows new potential target for CAR T cells to inhibit solid tumors

Gene expression signatures in lymph node cells play an active role in lymphoma development

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