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Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

Exercise training may slow tumor growth for females with breast cancer

Exercise training may slow tumor growth and improve outcomes for females with breast cancer - especially those treated with immunotherapy drugs - by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have found.

13 Apr 2021

Study compares effect of vaping and smoking on cells and DNA

Researchers have compared vape e-liquid samples and their aerosols to combustible cigarette smoke using Toxys’ ToxTracker range of in-vitro assays.

12 Apr 2021

A new way to predict positive outcomes of immunotherapy in patients with bladder cancer

Researchers have detected and validated groups of genes linked to immunotherapy resistance in patients with metastatic urothelial cancer of the bladder.

12 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

According to a study, DNA defects in the energy “factories” of a cell increase the chance of survival in patients suffering from bowel cancer.

9 Apr 2021

Researchers upend the models of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

From Vanderbilt University 8 Apr 2021

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Researchers have discovered how specific proteins ensure the rectification of errors introduced into the DNA when it replicates.

7 Apr 2021

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Deep learning algorithms can help classify breast lesions from ultrasound images

In 2020, the International Agency for Research on Cancer of the World Health Organization stated that breast cancer accounts for most cancer morbidities and mortalities in women worldwide.

7 Apr 2021

Tumor-inhibiting protein p53 boosts gene expression by bringing together nuclear speckles and DNA

Scientists at the University of Pennsylvania headed a group of researchers to unravel the functions of the so-called “nuclear speckles”.

6 Apr 2021

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

A pre-clinical study for melanoma and neuroblastoma shows that a customized tumor cell vaccine technique that targets Myc oncogenes coupled with checkpoint therapy produces an active immune response that bypasses antigen selection and immune privilege.

5 Apr 2021

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

A research team from Italy has discovered a pair of microRNA molecules that assist in maintaining a population of cancerous stem cells that fuel the growth of breast cancers and trigger tumor relapse after treatment.

5 Apr 2021

New mechanism of transcriptional regulators influences tumor development

The Wistar Institute scientists have discovered a novel mechanism of transcriptional regulation of cellular senescence that promotes the release of inflammatory molecules that, in turn, affect tumor growth by changing the surrounding microenvironment.

2 Apr 2021

Tumor News and Research

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Exercise training may slow tumor growth for females with breast cancer

Study compares effect of vaping and smoking on cells and DNA

A new way to predict positive outcomes of immunotherapy in patients with bladder cancer

New method can improve the drug testing process

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

Researchers upend the models of cancer metabolism

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

Deep learning algorithms can help classify breast lesions from ultrasound images

Tumor-inhibiting protein p53 boosts gene expression by bringing together nuclear speckles and DNA

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

High expression of cell death genes linked to increased risk of dying early from lung cancer

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

New mechanism of transcriptional regulators influences tumor development

Neurod4 gene found to be the key factor in nerve regeneration after spinal cord injury

Developing a new CRISPR technique

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

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