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Newly discovered protein could be an important target to prevent prostate cancer metastases

Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.

21 Jul 2020

Novel nano drug candidate kills triple negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

21 Jul 2020

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.

20 Jul 2020

Study shows how cells respond to nutrient deprivation

The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell's organelles as power plants, factories, roads, libraries, warehouses and more.

From Harvard Medical School 17 Jul 2020

Disseminated cancer cells hijack crucial iron micronutrients to survive

In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report.

17 Jul 2020

Rare inherited mutation in TP53 gene predisposes to a wide range of cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

17 Jul 2020

Study shows how breast cancer cells escape the immune system

Scientists have explained a new method that clearly shows how a crucial player in the body’s immune system is destroyed by breast cancer cells.

17 Jul 2020

Development of mammalian placenta depends upon simple twist of DNA

The development of the mammalian placenta depends upon an unusual twist that separates DNA's classic double helix into a single-stranded form, Yale researchers report July 15 in the journal Nature.

16 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

Researchers develop novel and promising approach for treatment of lung cancer

A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. The new study has been published in the July issue of Advanced Therapeutics.

16 Jul 2020

Researchers develop novel technology to detect cancer biomarkers

A new way of identifying cancer biomarkers has been developed by researchers at Lund University in Sweden. The new technology allows very sensitive, quick and cost-effective identification of cancer biomarkers. The research is published in Nature Communication Biology.

16 Jul 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020

UVA scientists identify oncogene responsible for glioblastoma

Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor.

15 Jul 2020

Golgi membrane protein drives growth and invasion of breast cancer

The cover for issue 28 of Oncotarget features Figure 5, "TMEM165 expression levels alters N-linked glycosylation," by Murali, et al., and reported that the TMEM165 protein was not detected in non-malignant matched breast tissues and was detected in invasive ductal breast carcinoma tissues by mass spectrometry.

15 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

Novel approach to analyze organ development through gene analysis in single cells

When cells develop, variations in the interaction of genes of an individual determine their fate. Such variations in genetic interactions can make the individual’s cells powerful against infection from viruses or enable the immune cells to kill the tumor cells.

14 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response.The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of a patient's immune system are re-engineered in the lab to attack cancer cells.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

Tumor News and Research

Newly discovered protein could be an important target to prevent prostate cancer metastases

Novel nano drug candidate kills triple negative breast cancer cells

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Study shows how cells respond to nutrient deprivation

Disseminated cancer cells hijack crucial iron micronutrients to survive

Rare inherited mutation in TP53 gene predisposes to a wide range of cancers

Study shows how breast cancer cells escape the immune system

Development of mammalian placenta depends upon simple twist of DNA

New, promising CAR T cell therapy results in exceptional patient recovery

Researchers develop novel and promising approach for treatment of lung cancer

Researchers develop novel technology to detect cancer biomarkers

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

UVA scientists identify oncogene responsible for glioblastoma

Golgi membrane protein drives growth and invasion of breast cancer

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Novel approach to analyze organ development through gene analysis in single cells

PET radiotracer is safe and effective for imaging malignant brain tumors

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

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