Tumor News and Research

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Location-Dependent Gene Expression in Ovarian Cancer: Insights from 3-D Models

Variations in gene activity based on where a cell is in a tumor have been discovered by researchers with the help of 3-D models of ovarian cancer tumors.

26 Jun 2023

New Genetic Marker Could Predict Lenvatinib Resistance in Hepatocellular Carcinoma

A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib.

23 Jun 2023

Loss of the Y Chromosome Impairs Body's Ability to Fight Cancer

According to recent Cedars-Sinai Cancer research, as men age, some of their cells lose the very feature that makes them biological males—the Y chromosome—and this loss impairs the body’s ability to fight cancer.

22 Jun 2023

Newly Found Disease Links Disruptions of Blood Formation, Immune System and Inflammation

In the quest to find the origin of the puzzling symptoms in four children, researchers from St. Anna Children's Cancer Research Institute, the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (ÖAW), and the Medical University of Vienna have discovered a completely new disease, linking disruptions of blood formation, the immune system, and inflammation.

22 Jun 2023

Photoacoustic Spectral Analysis Shows Promise for Noninvasive Diagnosis of Tumors

Tumors are not just isolated clumps of abnormal cells but are associated with more complex system known as the "tumor microenvironment" (TME).

14 Jun 2023

Virus Plays Important Role in Treating Glioblastoma

A potential advancement in the treatment of glioblastoma was noted by Howard Colman, MD, PhD, the Jon M. Huntsman Presidential Professor of Neuro-Oncology and co-leader of the Neurologic Cancers Disease Center and the Experimental Therapeutics CCSG program at Huntsman Cancer Institute, in a recently published manuscript.

13 Jun 2023

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

1 Jun 2023

Youth Gene "Chinmo" Could Link to Cancerous Processes

Chinmo, the gene responsible for the juvenile stage in insects, has been discovered by researchers. This gene is found in animals and could have a role in cancerous processes.

26 May 2023

Imaging Technology Provides New Understanding of Root Chemicals Responsible for Plant Growth

On a sunny springtime stroll through a park, it's easy to ignore the parts of plants that are hidden from view. Plant biologists see things differently.

26 May 2023

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

Researchers Elucidate the Exact Mechanism of Cell Death

24 May 2023

Molecular Method Reveals Whether or Not Bacteria Respond to Antibiotics Within Minutes

Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.

23 May 2023

New Insights into the Final Step of Cell Death

Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers at the University of Basel have now been able to elucidate the exact mechanism at the atomic level. They have published their results in Nature.

23 May 2023

Targeting Cellular Respiration for the Treatment of Glioblastoma

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Targeting cellular respiration as a therapeutic strategy in glioblastoma."

22 May 2023

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow.

18 May 2023

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

17 May 2023

Study Implicates RNA Molecules as New Players in Esophageal Cancer

Irregularities in the body's genetic coding to make proteins are linked to cancerous tumors. But most genetic material contains elements whose function isn't clear.

16 May 2023

Study Offers New Insights Into Neuroendocrine Transdifferentiation in Breast and Prostate Cancer Biology

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation."

15 May 2023

New Insights Into How Diverse Chromosomal Alterations Form and Drive Cancer Development

The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells.

12 May 2023

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.