Vaccine News and Research

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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Zika virus infection during pregnancy can cause severe abnormalities in the fetus

Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly. In a small proportion of cases, the disease may lead to miscarriage and perinatal death.

4 Sep 2020

Gut bacterium is linked to increased risk of stomach cancer

The bacterium Helicobacter pylori is linked to increased risk of stomach cancer, and is genetically highly variable. A new study by researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich explores the role played by this diversity in the early phase of infection in adult humans.

3 Sep 2020

Researchers identify an effective treatment for severe cases of COVID-19 infection

Scientists are trying to figure out how SARS-CoV-2 leads to a range of symptoms that appear to persist long after the active viral infection.

From Osaka University 1 Sep 2020

Study shows neutralizing antibodies can protect against SARS-CoV-2 virus

In May, a fishing vessel exited a port and returned with the first-ever proof that neutralizing antibodies offer protection from being re-infected by SARS-CoV-2.

1 Sep 2020

New COVID-19 mouse model helps advance vaccine development

A new COVID-19 mouse model developed at the University of North Carolina at Chapel Hill captures many of the features of human disease and has helped advance a COVID-19 vaccine candidate to clinical trial.

28 Aug 2020

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

Study uncovers how the immune system generates effective antibodies

An in-depth Garvan study of how the immune system generates effective antibodies provides new insights for vaccine design.

25 Aug 2020

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Given the global urgency of the COVID-19 pandemic, Microsoft's AI for Health program has stepped in to support the development and potential deployment of Vaxine's COVAX-19™ vaccine with a philanthropic grant.

25 Aug 2020

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

A new study by researchers at MassBiologics of UMass Medical School published in Nature Communications suggests that COVID specific IgA monoclonal antibodies may provide effective immunity in the respiratory system against the novel coronavirus - a potentially critical feature of an effective vaccine.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

New study shows promise for developing COVID-19 vaccine

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

24 Aug 2020

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

20 Aug 2020

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

From Harvard Medical School 20 Aug 2020

Surface structure of SARS-CoV-2 virus offers insights for development of therapeutics

At the start of a COVID-19 infection, the coronavirus SARS-CoV-2 docks onto human cells using the spike-like proteins on its surface. The spike protein is at the centre of vaccine development because it triggers an immune response in humans.

19 Aug 2020

Long-term opioid use in back-pain patients leads to production of anti-opioid antibodies

University of Wisconsin-Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies.

19 Aug 2020

Novel gene editing approach removes latent herpes simplex virus 1

Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.

19 Aug 2020

Researchers detect robust T cell response in patients with mild COVID-19 infection

Mild cases of COVID-19 pandemic can activate strong responses from memory T cells, even when detectable virus-specific antibody responses are absent.

19 Aug 2020

Study reveals why immunity boost from seasonal flu vaccines is not long lasting

A study from Emory Vaccine Center provides insights into why the boost in immunity from seasonal flu vaccination lasts for months but not years, unlike some childhood vaccinations.

14 Aug 2020

Study identifies a protein that facilitates spread of SARS-CoV-2 virus through cells

Eric Ross and Sean Cascarina, biochemistry and molecular biology researchers at Colorado State University, have released a research paper identifying a protein encoded by SARS-CoV-2, the virus that causes COVID-19, that may be associated with the quick spread of the virus through cells in the human body.

13 Aug 2020

Vaccine News and Research

Zika virus infection during pregnancy can cause severe abnormalities in the fetus

Gut bacterium is linked to increased risk of stomach cancer

Researchers identify an effective treatment for severe cases of COVID-19 infection

Study shows neutralizing antibodies can protect against SARS-CoV-2 virus

New COVID-19 mouse model helps advance vaccine development

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

New syringe technology for subcutaneous injection of viscous formulations

Study uncovers how the immune system generates effective antibodies

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

Researchers add a component to make cancer vaccine more effective

New study shows promise for developing COVID-19 vaccine

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

Surface structure of SARS-CoV-2 virus offers insights for development of therapeutics

Long-term opioid use in back-pain patients leads to production of anti-opioid antibodies

Novel gene editing approach removes latent herpes simplex virus 1

Researchers detect robust T cell response in patients with mild COVID-19 infection

Study reveals why immunity boost from seasonal flu vaccines is not long lasting

Study identifies a protein that facilitates spread of SARS-CoV-2 virus through cells

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