Vaccine News and Research

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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

UNC Charlotte Study: SARS-CoV-2 Variants BA.2.86 and JN.1 Show Minimal Immune Evasion

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

22 Jul 2024

Marginal Zone B Cells Unveiled as Key Players in TB Vaccine Strategy

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

16 Jul 2024

Breakthrough Study Reveals How Toxoplasma gondii Alters Host Cell Metabolism

Toxoplasma gondii is a parasite responsible for toxoplasmosis, a lifelong chronic infection prevalent in about 30% of the human population.

12 Jul 2024

Scientists develop first fully functional human immune system in mouse model

Researchers at The University of Texas Health Science Center in San Antonio have produced a mouse model that is humanized, complete with a human immune system and a gut microbiome that resembles that of a human being and is able to elicit particular antibody responses.

8 Jul 2024

Using Mobile Data to Track the Spread and Evolution of Superbugs

Key insights into the global spread, evolution, and resistance patterns of a major bacterium causing pneumonia and meningitis have been revealed through the combination of genomic data and human travel patterns over 14 years in South Africa.

4 Jul 2024

Discovery Reveals the Role of Interleukin-12 in Directing B-Cell Antibody Responses

B cells are known to generate antibodies through two different responses—an "emergency response" and an "everything is okay, let’s prepare for the future response," says Mark Shlomchik, UPMC Professor and Distinguished Professor of Immunology, University of Pittsburgh School of Medicine.

28 Jun 2024

AI-Driven Design of Soluble Protein Analogs for Drug Discovery and Antibody Development

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

24 Jun 2024

Study Reveals Immune Factors Behind COVID-19 Resistance in Some Individuals

As part of the first-ever COVID-19 human challenge study, researchers from the Wellcome Sanger Institute, University College London (UCL), Imperial College London, the Netherlands Cancer Institute, and their collaborators examined immune responses against SARS-CoV-2 infection in healthy adult volunteers using single-cell sequencing.

20 Jun 2024

Exploring the Use of Weakened Viruses for Cancer Treatment

Scientists at Northwestern Medicine have found that an attenuated virus can aid in the elimination of cancer in mice. Furthermore, mice given this virus treatment had a higher lifetime tumor-prevention rate.

12 Jun 2024

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

16 May 2024

UNC Researchers Create Key Tool for Kaposi Sarcoma Drug Development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

30 Apr 2024

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

An interview with Dr. Rajas Warke, HiMedia Laboratories' youngest director.

From Himedia Laboratories Private Limited 29 Apr 2024

Revealing the Genetic Mechanisms Driving SARS-CoV-2 Variants

The SARS-CoV-2 virus, responsible for COVID-19, exhibits a troubling tendency to produce variants frequently.

23 Apr 2024

Breakthrough RNA-Based Vaccine Strategy Offers Universal Protection

Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.

16 Apr 2024

Genetic Link to Persistent HPV Infections Identified

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.

15 Apr 2024

Study Reveals Genetic Underpinnings for Cervical Cancer Risk from Persistent HPV Infections

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.

12 Apr 2024

Engineering Live Vaccines for Improved Immune Response

Bacterial proteins frequently outsmart the immune system, making it more challenging to fight off the bacteria that cause illnesses like staph infections.

5 Apr 2024

Scientists Pioneer mRNA Approach to Target Alzheimer's Protein

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

29 Mar 2024

Federal Regulation Urged for Direct-to-Consumer Microbiome Tests

Scientific research has linked a person's microbiome to everything from gut and mental health to immunity and predisposition to cancer.

25 Mar 2024

Metabolic Insights into Immune Cell Activation and Response

Researchers from Children's Hospital of Philadelphia identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.

18 Mar 2024

Vaccine News and Research

UNC Charlotte Study: SARS-CoV-2 Variants BA.2.86 and JN.1 Show Minimal Immune Evasion

Marginal Zone B Cells Unveiled as Key Players in TB Vaccine Strategy

Breakthrough Study Reveals How Toxoplasma gondii Alters Host Cell Metabolism

Scientists develop first fully functional human immune system in mouse model

Using Mobile Data to Track the Spread and Evolution of Superbugs

Discovery Reveals the Role of Interleukin-12 in Directing B-Cell Antibody Responses

AI-Driven Design of Soluble Protein Analogs for Drug Discovery and Antibody Development

Study Reveals Immune Factors Behind COVID-19 Resistance in Some Individuals

Exploring the Use of Weakened Viruses for Cancer Treatment

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

UNC Researchers Create Key Tool for Kaposi Sarcoma Drug Development

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Revealing the Genetic Mechanisms Driving SARS-CoV-2 Variants

Breakthrough RNA-Based Vaccine Strategy Offers Universal Protection

Genetic Link to Persistent HPV Infections Identified

Study Reveals Genetic Underpinnings for Cervical Cancer Risk from Persistent HPV Infections

Engineering Live Vaccines for Improved Immune Response

Scientists Pioneer mRNA Approach to Target Alzheimer's Protein

Federal Regulation Urged for Direct-to-Consumer Microbiome Tests

Metabolic Insights into Immune Cell Activation and Response

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

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