A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.
A recent study elaborates how B lymphocytes decide between various cell fates to balance the magnitude of the acute immune responses.
Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body's own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.
The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.
COVID-19 vaccines are effective at preventing hospitalizations and emergency department visits caused by the Delta variant, according to data from a national study.
According to scientists, the Delta variant of SARS-CoV-2 has likely spread through its capability to avoid neutralizing antibodies and its heightened infectivity.
A research team at the RIKEN Center for Emergent Matter Science in Japan has developed a diagnostic system that can rapidly and sensitively measure the amount of antibodies in the blood that can protect us from SARS-CoV-2, the virus that causes COVID-19.
Tiny synthetic particles known as dendrimers have been shown to avoid detection by our immune system and so could be used to develop a new system to deliver drugs into the body without triggering a reaction.
Rutgers Professor Lewis Nelson is available to discuss the dangers of people taking the livestock deworming drug ivermectin to try to treat COVID-19.
The efficacy of multiple vaccine candidates that target three filoviruses responsible for life-threatening infections to humans has been demonstrated in monkeys.
Cells produce exosomes, the nano-sized biological capsules, to protect and courier delicate molecules across the body. The capsules are hard enough to resist enzymatic breakdown and acidic and temperature fluctuations in the bloodstream and gut, which makes them a major candidate for drug delivery.
A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.
Although the development and increasingly widespread availability of effective and safe vaccines provides the greatest hope for the future recovery from the increasingly devastating COVID-19 pandemic, genomic surveillance is emerging as a vital necessity to achieve effective mitigation and containment.
Despite causing a surge in infections this summer that has resulted in thousands of hospitalizations and deaths, the delta variant of the virus that causes COVID-19 is not particularly good at evading the antibodies generated by vaccination, according to a study by researchers at Washington University School of Medicine in St. Louis.
Scientists have discovered that individuals recovering from COVID-19 produce identical clones, or groups, of antibody-producing white blood cells.
Scientists have created an “atlas” that charts how 152 different antibodies attack a major piece of the SARS-CoV-2 machinery, the spike protein.
Researchers created a “nanobody”, a small fragment of a llama antibody, that can evade human cytomegalovirus as it hides away from the immune system.
A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.
Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.
Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.
The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.