Vaccine News and Research

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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

The immune system can play a key role in improving recovery from heart attacks

International research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

Researchers explore the reproduction of adenoviruses in cells

An adenovirus infection can be potentially life-threatening, especially for children after a stem cell transplant.

14 Jul 2020

Analysis of nearly 300 new SARS-CoV-2 antibodies reveals a common feature

An analysis of nearly 300 recently identified human SARS-CoV-2 antibodies uncovered a gene frequently used in antibodies that most effectively target the virus. The results contribute to growing structural insight that will be needed for successful vaccine development against SARS-CoV-2.

14 Jul 2020

Single dose of flu drug can limit the spread of the illness within households

A single dose of the flu drug baloxavir marboxil can reduce the spread of the illness within households, new research concludes.

14 Jul 2020

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

14 Jul 2020

New technology generates immune response by delivering antigens to APCs in the spleen

Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

New mutation in common flu subtype helps evade immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

13 Jul 2020

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre at the University of Saskatchewan and Temple University have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals.

10 Jul 2020

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Researchers at the Francis Crick Institute have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design.

10 Jul 2020

Researchers identify protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

6 Jul 2020

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

3 Jul 2020

Flame sterilization of shake-flasks affects cell culture

Researchers commonly culture bacteria for many purposes, such as to screen pharmaceuticals and manufacture vaccines. In these cases, shake flasks have been commonly and generally used for over 90 years to cultivate microbes.

2 Jul 2020

Even the sickest COVID-19 patients produce T cells to fight back the virus

A new study from researchers at La Jolla Institute for Immunology and Erasmus University Medical Center shows that even the sickest COVID-19 patients produce T cells that help fight the virus.

1 Jul 2020

Novel vaccine targeting senescent cells mitigates metabolic disorders in obese mice

Aging is a multifaceted process that affects our bodies in many ways. In a new study, researchers from Osaka University developed a novel vaccine that removes aged immune cells and then demonstrated an improvement of diabetes-associated metabolic derangements by vaccinating obese mice.

From Osaka University 1 Jul 2020

Vaccine News and Research

The immune system can play a key role in improving recovery from heart attacks

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

Researchers explore the reproduction of adenoviruses in cells

Analysis of nearly 300 new SARS-CoV-2 antibodies reveals a common feature

Single dose of flu drug can limit the spread of the illness within households

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

New technology generates immune response by delivering antigens to APCs in the spleen

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

New mutation in common flu subtype helps evade immune response

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Researchers identify protective antibodies for rare, polio-like disease in children

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

Flame sterilization of shake-flasks affects cell culture

Even the sickest COVID-19 patients produce T cells to fight back the virus

Novel vaccine targeting senescent cells mitigates metabolic disorders in obese mice

Study provides roadmap for developing effective vaccine against Staphylococcal infections

COVID-19 virus can infect heart cells in a lab dish, study shows

Experts identify steps to expand, improve SARS-CoV-2 serology tests

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